Abstract
BIOCHEMICAL estimation of acid or alkaline phosphatase activity of the prostate sometimes indicates no change under experimental conditions, or in some cases an increase or decrease. Histochemical examination of the gland under such conditions can show fundamental alterations in distribution of phosphatase activity that are not reflected in the biochemical estimations, which can therefore give rise to most misleading conclusions. Some examples will illustrate this.
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See also Brandes and Bourne, Brit. J. Exp. Pathol., [35, 577 (1954)].
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BRANDES, D., BOURNE, G. Histochemical Control in Biochemical Estimation of Prostatic Phosphatase Activity. Nature 175, 637–638 (1955). https://doi.org/10.1038/175637a0
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DOI: https://doi.org/10.1038/175637a0
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