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Action of Squalene upon Carcinogenic Hydrocarbons

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Abstract

SQUALENE is an unsaturated triterpenoid hydrocarbon which was originally isolated from the liver oil of the shark1. Among its other occurrences, it was found to be present in the fat from ovarian dermoid cysts2. In an investigation on the role of sebum in carcinogenesis, squalene was found to be present in horse smegma and in human ear wax and hair oil3,4. MacKenna and co-workers found it in skin surface sebum5.

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References

  1. Tsyjimoto, M., Indust. Eng. Chem., 8, 889 (1916).

    Article  Google Scholar 

  2. Dimter, A., Z. Physiol. Chem., 270, 247 (1941).

    Article  CAS  Google Scholar 

  3. Sobel, H., and Plaut, A., Cancer Res., 9, 629 (1949).

    Google Scholar 

  4. Sobel, H., J. Inv. Derm., 13, 333 (1949).

    Article  CAS  Google Scholar 

  5. MacKenna, R. M. B., Wheatley, V. R., and Wormall, A., J. Inv. Derm., 15, 33 (1950).

    Article  CAS  Google Scholar 

  6. Sobel, H., Marmorston, J., and Arzangoolian, H., Science, 119, 3101 (1954).

    Article  Google Scholar 

  7. Bernheim, M. L. C., Bernheim, F., and Wilbur, K. M., Nature, 172, 306 (1953).

    Article  ADS  CAS  Google Scholar 

  8. Mueller, G. C., Miller, J. A., and Rusch, H. P., Cancer Res., 5, 401 (1945).

    CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Biochemistry, Division of Laboratories,

    HARRY SOBEL & JESSIE MARMORSTON

  2. the Institute for Medical Research, Cedars of Lebanon Hospital, Los Angeles, 29, California

    HARRY SOBEL & JESSIE MARMORSTON

Authors
  1. HARRY SOBEL
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  2. JESSIE MARMORSTON
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SOBEL, H., MARMORSTON, J. Action of Squalene upon Carcinogenic Hydrocarbons. Nature 174, 553–554 (1954). https://doi.org/10.1038/174553c0

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