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Alternate Pathways of Glycerol Oxidation in Acetobacter suboxydans

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Abstract

A PREVIOUS publication from this laboratory1 has reported in detail the rapid oxidation of glycerol to dihydroxyacetone by resting whole cells of A. suboxydans 621, at pH 6.0. This conversion proceeds more slowly beyond the dihydroxyacetone stage. In cell-free extracts with triphenyltetrazolium chloride as the electron acceptor, glycerol is oxidized at a rate comparable to the oxidation of dihydroxyacetone, with the pH optimum about 8.5. This contrasting behaviour has been found to be due to the presence of two major oxidative routes for glycerol oxidation, one phosphorylative, the other independent of phosphate, as shown in Table 1. With cell-free extracts at pH 8.5, adenosine triphosphate is obligatory (in kinase systems) not only for the oxidation of glycerol but also for dihydroxyacetone, glucose, ribose or erythritol.

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Author notes

  1. JENS G. HAUGE: Fellow of the Royal Norwegian Council for Scientific and Industrial Research.

Authors and Affiliations

  1. Department of Chemistry and Science Research Institute, Oregon State College, Corvallis, Oregon

    JENS G. HAUGE, TSOO E. KING & VERNON H. CHELDELIN

Authors
  1. JENS G. HAUGE
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  2. TSOO E. KING
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  3. VERNON H. CHELDELIN
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HAUGE, J., KING, T. & CHELDELIN, V. Alternate Pathways of Glycerol Oxidation in Acetobacter suboxydans . Nature 174, 1104–1105 (1954). https://doi.org/10.1038/1741104a0

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