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Enzymatic Conversion of Salicylhydroxamic Acid to Salicylamide

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Abstract

AFTER the administration of Salicylhydroxamic acid to rats, we have been able to isolate conjugates of Salicylhydroxamic acid and salicylamide from the urine1. In the intact animal, Salicylhydroxamic acid is therefore partly metabolized to salicylamide. In the present communication, the enzymatic transformation of Salicylhydroxamic acid to salicylamide in vitro is reported.

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References

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Authors and Affiliations

  1. Department of Physiology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada

    JULIUS LOWENTHAL

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  1. JULIUS LOWENTHAL
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LOWENTHAL, J. Enzymatic Conversion of Salicylhydroxamic Acid to Salicylamide. Nature 174, 36–37 (1954). https://doi.org/10.1038/174036a0

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