Abstract
ALTHOUGH the mechanism of the formation of inosinic acid from hypoxanthine1 or glycine and formic acid2, and the phosphorylation of adenosine to form 5-adenylic acid3,4, have been studied in cell-free systems, the participation of adenine in nucleotide synthesis has received little attention. During an investigation of the pathway of incorporation of radioactive adenine into ribonucleic acid by in vitro systems in this laboratory, it was found that homogenates of pigeon liver were very active in the formation of acid-soluble adenine nucleotides within a short time.
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GOLDWASSER, E. Formation of Adenine Nucleotides from Adenine by Pigeon Liver Homogenates. Nature 171, 126–127 (1953). https://doi.org/10.1038/171126a0
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DOI: https://doi.org/10.1038/171126a0
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