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Histochemical Differentiation of cis-trans 1-2 Glycols

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Abstract

SINCE McManus1 introduced his periodic acid technique for histochemical localization of the 1-2 glycol linkage, the field has been well investigated Other techniques have been devised, utilizing both periodic acid2 and lead tetraacetate3–5 to split the carbon–carbon single bond of the glycol to produce leucofuchsin-demonstrable aldehyde radicals. In all these studies, however, little attention was paid to the linkage itself but rather to the parent compound. The present investigation was undertaken to study the cis-trans isomerism of the 1-2 glycol linkage during this oxidative process.

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Authors and Affiliations

  1. Department of Anatomy, School of Medicine, University of Oklahoma,

    JOHN F. LHOTKA

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  1. JOHN F. LHOTKA
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LHOTKA, J. Histochemical Differentiation of cis-trans 1-2 Glycols. Nature 170, 751–752 (1952). https://doi.org/10.1038/170751a0

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