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The Rabbit Lumbrical: a New Isolated Mammalian Nerve–Muscle Preparation

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Abstract

THE rat diaphragm phrenic nerve preparation1 enabled mammalian muscle to be studied under precise conditions of drug and ion concentration, but is insensitive to decamethonium (C10). The object of this communication is to describe a new isolated mammalian nerve–muscle preparation which does not suffer from this disadvantage. Several muscles in the feet of rabbits and cats are suitable; but the medial lumbrical of the rabbit's hind foot has been found most satisfactory. It is usually about 18 mm. long and 1 mm. in diameter under physiological tension.

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References

  1. Bulbring, E., Brit. J. Pharmacol., 1, 38 (1946).

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Authors and Affiliations

  1. Division of Pharmacology, University of California Medical Center, San Francisco, California

    D. J. JENDEN, K. KAMIJO & D. B. TAYLOR

Authors
  1. D. J. JENDEN
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  2. K. KAMIJO
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  3. D. B. TAYLOR
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JENDEN, D., KAMIJO, K. & TAYLOR, D. The Rabbit Lumbrical: a New Isolated Mammalian Nerve–Muscle Preparation. Nature 168, 880–881 (1951). https://doi.org/10.1038/168880b0

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