Abstract
THE isolation of 17-hydroxycorticosterone and 17-hydroxy-11-dehydrocorticosterone from hog adrenals has been described by Kuizenga et al.1,2. The method described involved many stages and an extensive series of benzene–water partitions to effect the separation and isolation of these compounds, the fractionation being followed by means of biological assays.
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References
Kuizenga, M. H., Wick, A. N., Ingle, D. J., Nelson, J. W., and Cartland, G. F., J. Biol. Chem., 147, 561 (1943).
Kuizenga, M. H., Nelson, J. W., Lyster, S. C., and Ingle, D. J., J. Biol. Chem., 160, 15 (1945).
Zaffaroni, A., Burton, R. B., and Keutmann, E. H., Science, 111, 6, (1950).
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BAKER, P., DOBSON, F. & STROUD, S. Isolation of 17-Hydroxycorticosterone and 17-Hydroxy-11-dehydrocorticosterone from Hog Adrenals. Nature 168, 114–115 (1951). https://doi.org/10.1038/168114b0
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DOI: https://doi.org/10.1038/168114b0
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