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Stimulation by Insulin of in vitro Fat Synthesis by Mammary Tissue studied with Carbon-14 and Tritium

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Abstract

RESPIRATORY observations have been interpreted1 as indicating that lactating mammary gland slices are able to utilize acetate for net fatty-acid synthesis in vitro, either as sole substrate (ruminants: sheep, goat, cow) or in the presence of glucose (non-ruminants: rat, rabbit). Tissue respiration measurements have, moreover, led to the further conclusion2–4 that insulin, added in vitro, causes a marked stimulation of fat synthesis by lactating mammary gland slices from rat, rabbit and mouse.

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References

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Authors and Affiliations

  1. National Institute for Research in Dairying, Shinfield, Nr. Reading

    JUDITH H. BALMAIN, S. J. FOLLEY & R. F. GLASCOCK

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  1. JUDITH H. BALMAIN
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  2. S. J. FOLLEY
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  3. R. F. GLASCOCK
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BALMAIN, J., FOLLEY, S. & GLASCOCK, R. Stimulation by Insulin of in vitro Fat Synthesis by Mammary Tissue studied with Carbon-14 and Tritium. Nature 168, 1083–1084 (1951). https://doi.org/10.1038/1681083a0

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