Abstract
Genetic studies in mice, worms and flies indicate that the synaptic protein UNC-13 plays a central role in the regulation of vesicle fusion.
References
Südhof, T. C. Nature 375, 645–653 (1995).
Augustine, G. J. et al. J. Physiol. (Lond.) 520, 33–42 (1999).
Weber, T. et al. Cell 92, 759–772 (1998).
Augustin, I., Rosenmund, C., Südhof, T. C. & Brose, N. Nature 400, 457–461 (1999).
Richmond, J. E., Davis, W. S. & Jorgensen, E. M. Nat. Neurosci. 2, 959–964 (1999).
Aravamudan, B., Fergestad, T., Davis, W. S., Rodesch, C. K. & Broadie, K. Nat. Neurosci. 2, 965–971 (1999).
Brenner, S. Genetics 77, 71–94 (1974).
Kazanietz, M. G. et al. J. Biol. Chem. 269, 11590–11594 (1994).
Betz, A. et al. Neuron 21, 123–136 (1998).
Hori, T., Takai, Y. & Takahashi, T. J. Neurosci. 19, 7262–7267 (1999).
Katz, B. The Release of Neural Transmitter Substances (Liverpool Univ. Press, Liverpool, 1969).
Quastel, D. M., Hackett, J.T. & Cooke, J. D. Science 172, 1034–1036 (1971).
Heuser, J. E. & Reese, T. S. J. Cell Biol. 57, 315–344 (1973).
Xu, Z., Sato, K. & Wickner, W. Cell 93, 1125–1134 (1998).
Hay, J. C. et al. Nature 374, 173–177 (1995).
Betz, A., Okamoto, M., Benseler, F. & Brose, N. J. Biol. Chem. 272, 2520–2526 (1997).
Sassa, T. et al. J. Neurosci., 19, 4772–4777 (1999).
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Tokumaru, H., Augustine, G. UNC-13 and neurotransmitter release. Nat Neurosci 2, 929–930 (1999). https://doi.org/10.1038/14710
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DOI: https://doi.org/10.1038/14710
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