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Close encounters of the LIM-kinase

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Abstract

During cell movement, new actin structures are formed, under the orders of the small GTPase Rac. One of Rac’s orders is to inhibit the depolymerization of existing actin filaments. A chain of events from Rac to the inhibition of actin depolymerization has now been forged.

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Figure 1: Regulation of actin by the GTPase Rac.

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Chernoff, J. Close encounters of the LIM-kinase. Nat Cell Biol 1, E115–E117 (1999). https://doi.org/10.1038/12942

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