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Anxiety: at the intersection of genes and experience

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Abstract

Human anxiety disorders arise from a combination of genetic vulnerability and traumatic experience. Mice with a GABAA receptor mutation may provide a model for these disorders.

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Figure 1: Individual variability in response to anxiety-provoking environments.
Figure 2: Simplified neural circuit mediating fear.

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Authors and Affiliations

  1. Departments of Psychology (M.G.C. & M.S.F.) and Neurobiology (S.G.A.), University of California, Los Angeles, 90095-1563, California, USA

    Stephan G. Anagnostaras, Michelle G. Craske & Michael S. Fanselow

Authors
  1. Stephan G. Anagnostaras
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  2. Michelle G. Craske
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  3. Michael S. Fanselow
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Anagnostaras, S., Craske, M. & Fanselow, M. Anxiety: at the intersection of genes and experience. Nat Neurosci 2, 780–782 (1999). https://doi.org/10.1038/12146

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