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Stress fibres take shape

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Abstract

The GTPase Rho is well known for its ability to induce the assembly of stress fibres. Two interacting targets of Rho, ROCK and Dia1, have been found to act in concert to mediate this response to Rho.

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Figure 1: A model for how ROCK and Dia1 cooperate to mediate Rho-induced stress-fibre formation.

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Authors and Affiliations

  1. Ludwig Institute for Cancer Research, University College London Branch, 91 Riding House Street, London, W1P 8BT, UK

    Anne J. Ridley

  2. Department of Biochemistry and Molecular Biology, University College London, Gower Street, London, WC1E 6BT, UK

    Anne J. Ridley

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  1. Anne J. Ridley
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Correspondence to Anne J. Ridley.

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Ridley, A. Stress fibres take shape. Nat Cell Biol 1, E64–E66 (1999). https://doi.org/10.1038/11034

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