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Emerging targets for anti-inflammatory therapy

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Abstract

Cytokines mediate acute and chronic inflammatory processes in disease. A new target for anti-inflammatory therapy has now been revealed, in the form of a kinase that promotes translation of specific cytokine messenger RNA species into proteins.

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Figure 1: Regulation of cytokine genes by the p38 MAP-kinase pathway

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Authors and Affiliations

  1. Department of Immunology, The Scripps Research Institute, La Jolla, 92037, California, USA

    J. Han & R. J. Ulevitch

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  1. J. Han
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  2. R. J. Ulevitch
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Correspondence to R. J. Ulevitch.

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Han, J., Ulevitch, R. Emerging targets for anti-inflammatory therapy. Nat Cell Biol 1, E39–E40 (1999). https://doi.org/10.1038/10032

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