Skip to main content
SpringerLink
Log in

Canine Visceral Leishmaniosis in Anastácio, Mato Grosso do Sul State, Brazil

  • Published:
Veterinary Research Communications Aims and scope Submit manuscript

Abstract

Canine visceral leishmaniosis (CVL) may be an important factor preceding human outbreaks of the disease. We report that the prevalence of canine visceral leishmaniosis infection has been increasing in recent years in Anastácio town, located in the central western region of Brazil. Serological investigations showed that 75.3% of dogs presented antibody titres ranging from 1/40 to 1/160 in the indirect immunofluorescence antibody test (IFAT). Bone marrow and lymph node aspirates provided positive cultures and furnished parasites for enzymological and serological typing in 42.5% and 41.1% of the cases, respectively. All the strains were typed asLeishmania (L.) chagasi. This is primarily a canine disease that spills over into the human population as a zoonosis. The study showed the epidemiological features of the infection in a region in which the problem of visceral leishmaniosis has been underestimated.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

REFERENCES

  • Abranches, P., Campino, L. and Santos-Gomes, G.M., 1998. Leishmaniose canina. Novos conceitos de epidemiologia e imunopatologia e seus reflexos no controle da leishmaniose visceral humana. Acta Médica Portuguesa, 11, 871-875

    Google Scholar 

  • Alencar, J.E., 1961. Profilaxia do calazar no Ceará, Brasil. Revista do Instituto de Medicina Tropical de São Paulo, 3, 175-180

    Google Scholar 

  • Alencar, J.E., 1963. Influência da determinação sobre a incidência do calazar humano no Ceará. Novos dados. Revista Brasileira de Malariologia, 15, 417-424

    Google Scholar 

  • Chagas, E., 1936. Primeira verificação em indivíduo vivo, da leishmaniose visceral no Brasil. Brasil Medical, 50, 221-222

    Google Scholar 

  • Chagas, E. and Chagas, H.W., 1937. Notas sobre epidemiologia da leishmaniose visceral americana em Mato Grosso. O. Hospital (Rio de Janeiro), 13, 471-480

    Google Scholar 

  • Cupolilo, E., Grimaldi, G. Jr., Momen, H. and Beverley, S.M., 1995. A general classification of New World Leishmania using numerical zymotaxonomy. American Journal of Tropical Medicine and Hygiene, 50, 296-311

    Google Scholar 

  • Deane, L.M., 1956. Leishmaniose visceral no Brasil. Serviço Nacional de Educação Sanitária, Rio de Janeiro, 162p

  • Deane, L.M. and Deane, M.P., 1954. Encontro de Leishmania nas vísceras e na pele de uma raposa, em zona endêmica de calazar, nos arredores de Sobral, Ceará. O Hospital (Rio de Janeiro), 45, 419-421

    Google Scholar 

  • Decker-Jackson, J.E. and Tang, D.B., 1982. Identification of Leishmania spp. by radiorespirometry II. A statistical method of data analysis to evaluate the reproducibility and sensitivity of the technique. In: M.L. Chance and B.C. Walton (eds), Biochemical characterization of Leishmania. Proceedings of a workshop held at the Pan American Health Organization, Geneva, (UNDP/World Bank/WHO), 205-245

  • Dietze, R., Barros, G.B., Teixeira, L., Harris, J., Hichelson, K., Falqueto, A. and Corey, R., 1997. Effect of eliminating seropositive canines on the transmission of visceral leishmaniasis in Brasil. Clinical Infectious Diseases, 25, 1240-1242

    Google Scholar 

  • Ellis, J.T. and Crampon, J.M., 1981. Differences between Leishmania (Leishmania) chagasi, L. (L.) infantum and L. (L.) donovani as shown by DNA fingerprint. Memórias do Instituto Oswaldo Cruz, 86, 479-481

    Google Scholar 

  • Gonçalves da Costa, S.C. and Lagrange, P.H., 1981. Development of cell mediated immunity to flagellar antigens and acquired resistance to infection by Trypanosoma cruzi in mice. Memórias do Instituto Oswaldo Cruz, 76, 367-381

    Google Scholar 

  • Guimarães, M.S.C., Giovannini, V.L. and Camargo, M.E., 1974. Antigenic standartization for mucocutaneous leishmaniasis immunofluorescence test. Revista do Instituto de Medicina Tropical de São Paulo, 16, 145-158

    Google Scholar 

  • Marques da Cunha, A. and Chagas, E., 1937. Leishmaniose visceral americana. O. Hospital (Rio de Janeiro), 11, 1-3

    Google Scholar 

  • Marzochi, M.C.A., Coutinho, S.G., Souza, W.J.S., Toledo, L.M., Grimaldi, G. Jr., Momen, H., Pacheco, R.S., Saboza, P.C., Souza, M.A., Rangel, F.B. Jr. and Tramontano, N., 1985. Canine visceral leishmaniasis in Rio de Janeiro, Brasil. Clinical, parasitological, therapeutical and epidemiological findings (1977–1983). Memórias do Instituto Oswaldo Cruz, 80, 349-357

    Google Scholar 

  • Mauricio, I.L., Howard, M.K., Stothard, J.R. and Miles, MA., 1999. Genomic diversity in the Leishmania donovani complex. Parasitology, 119, 237-246

    Google Scholar 

  • Mauricio, I.L., Stothard, J.R. and Miles, M.A., 2000. The strange case of Leishmania chagasi. Parasitology Today, 16, 188-189

    Google Scholar 

  • Mazza, S., 1926. Leishmaniosis tegumentar y visceral. Boletin de Instituto Clinico Quirurgica (Buenos Aires), 2, 209-216

    Google Scholar 

  • Migone, L.E., 1913. Un caso de kala-azar à Asuncion (Paraguay). Bulletin de la Societé de Pathologie Exótique, 6, 118-120

    Google Scholar 

  • Novy, F.G. and MacNeal, W.J., 1904. On the cultivation of Trypanosoma brucei. Journal of Infections Diseases, 1, 1-30

    Google Scholar 

  • Padilla, A.M., Marco, J.D., Diosque, P., Segura, M.A., Mora, M.C., Fernandez, M.M., Malchiodi, E.L. and Basombrio, M.A., 2002. Canine infection and the possible role of dogs in the transmission of American tegumentary leishmaniosis in Salta, Argentina. Veterinary Parasitology, 110, 1-10

    Google Scholar 

  • Penna, H.A., 1934. Leishmaniose visceral no Brasil. Brasil Medico, 48, 949-950

    Google Scholar 

  • Sherlock, I.A., 1969. Observações sobre calazar em Jacobina Bahia. I. histórico e dados preliminares. Revista Brasilieria da Malariologia e Doenças Tropicais, 21, 523-524

    Google Scholar 

  • Sherlock, I.A. and Almeida, S.P., 1970. Observações sobre o calazar em Jacobina, Bahia. V — Resultados de medidas profiláticas. Revista Brasilieria da Malariologia e Doenças Tropicais, 22, 715-728

    Google Scholar 

  • Silva, E.S., Rosco, E.H., Arruda, L.Q., Gontijo, C.M.F., Pacheco, R.S. and Brazil, R.P., 2001. Leishmaniose visceral canina: estudo clínico-epidemiológico e diagnóstico. Canine visceral leishmaniasis: clinical epidemiological study and diagnosis. Revista Brasileira de Medicina Veterinaria, 23, 111-116

    Google Scholar 

  • Torrealba, J.W., 1959. Considerações sobre a epidemiologia de la leishmaniose visceral en Venezuela. Gaceta Médica Caracas, 72, 99-115

    Google Scholar 

  • Vieira, J.B.F. and Coelho, G.E., 1998. Leishmaniose visceral ou calazar: aspectos epidemiológicos e de controle. Revista da Sociedade Brasileira de Médicina Tropical, 31, 85-92

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Departamento de Patologia, Laboratório de Parasitologia Humana, Universidade Federal de Mato Grosso do Sul, Brazil

    V.M.C.L. Cortada, M.E.C. Doval, M.A.A. Souza Lima & E.T. Oshiro

  2. Departamento de Protozoologia, Laboratório de Imunomodulação, Instituto Oswaldo Cruz –, Fundação Oswaldo Cruz, Brazil

    V.M.C.L. Cortada, A.L. Abreu-Silva, C.S.F. Souza, F.O. Cardoso, T. Zaverucha do Valle, K.S. Calabrese & S.C. Gonçalves da Costa

  3. Departamento de Imunologia, Laboratório de Pesquisas em Leishmaniose, Instituto Oswaldo Cruz –, Fundação Oswaldo Cruz, Brazil

    C.R.V. Meneses & E. Cupolilo

  4. Laboratório de Leishmanioses, Centro de Pesquisas René Rachou, Fundaça~o Oswaldo Cruz, Brazil

    R.P. Brazil

Authors
  1. V.M.C.L. Cortada
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. M.E.C. Doval
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. M.A.A. Souza Lima
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. E.T. Oshiro
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. C.R.V. Meneses
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. A.L. Abreu-Silva
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. E. Cupolilo
    View author publications

    You can also search for this author in PubMed Google Scholar

  8. C.S.F. Souza
    View author publications

    You can also search for this author in PubMed Google Scholar

  9. F.O. Cardoso
    View author publications

    You can also search for this author in PubMed Google Scholar

  10. T. Zaverucha do Valle
    View author publications

    You can also search for this author in PubMed Google Scholar

  11. R.P. Brazil
    View author publications

    You can also search for this author in PubMed Google Scholar

  12. K.S. Calabrese
    View author publications

    You can also search for this author in PubMed Google Scholar

  13. S.C. Gonçalves da Costa
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Cortada, V., Doval, M., Souza Lima, M. et al. Canine Visceral Leishmaniosis in Anastácio, Mato Grosso do Sul State, Brazil. Vet Res Commun 28, 365–374 (2004). https://doi.org/10.1023/B:VERC.0000035014.80785.b7

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1023/B:VERC.0000035014.80785.b7

Search

Navigation