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Multiple primary malignant neoplasms in urologic patients

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Abstract

Methods: Second primary cancers constitute approximately 9–10% of malignancies diagnosed in the United States. We aimed to show the risk and incidance of second primary tumor occuring associated to urologic tumors and show the distrubution of tumors in Tracia region. We retrospectively examined the patients' files with the diagnosis of malignant disease between the years 1985–2000. Hazard function analysis was performed to estimate the relative risk of secondary malignancy occuring. Age, sex and tumor number were examined to find out if they affect on mortality rate. Results: A total number of 25 MPMNs were diagnosed. In 52 percent of the cases the second primary neoplasm developed within six months. The relative risk of development of a second neoplasm is found as increasing 1.111 times per month. The incidence of secondary malignancy occuring in the patients with one tumor was found as 6.31%. Age (p < 0.001) and tumor number (p < 0.001) are found as statistically effective predictor on mortality rate where the sex is not. Conclusions: In the patients with a primary tumor not only the metastasis must be investigated but also second primary tumors should be taken in to consideration.

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Authors and Affiliations

  1. Department of Urology, Trakya University Medical Faculty Hospital, Edirne, Turkey

    Osman Inci, Esat Kaya, Bulent Alagol, Irfan Huseyin Atakan, Sabahattin Aydin & Hasan Ereselli

  2. Altinkoy Sitesi B-blok Daire:3 Kutlutas, 22030, Edirne, Turkey

    Esat Kaya

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  1. Osman Inci
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  2. Esat Kaya
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  3. Bulent Alagol
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  4. Irfan Huseyin Atakan
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  5. Sabahattin Aydin
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  6. Hasan Ereselli
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Correspondence to Esat Kaya.

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Inci, O., Kaya, E., Alagol, B. et al. Multiple primary malignant neoplasms in urologic patients. Int Urol Nephrol 36, 1–4 (2003). https://doi.org/10.1023/B:UROL.0000032673.34011.7d

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  • DOI: https://doi.org/10.1023/B:UROL.0000032673.34011.7d

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