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Impact of clinical and histopathological factors on outcome of egyptian patients with crescentic glomerulonephritis

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Abstract

This study included 128 patients withcrescentic glomerulonephritis (CGN) havingsufficient clinical and histopathological dataand were followed up in our institute for amean period of 34 ± 28 months. There were 49males and 79 females with mean age 22.7 ± 14years. We studied the effect of clinical,laboratory and histopathological parameters onkidney function and patient survival at the endpoint of the study. The multivariate analysisrevealed that serum creatinine at presentation,nephrotic range proteinuria during the followup period, percentage of glomeruli affected bycrescents, percentage of fibrous crescents andabsence of cellular infiltration weresignificant risk factors affecting the kidneyfunction at termination of the study. The onlyrisk factor which correlated significantly withthe patient mortality was the serum creatinineat last follows up.

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El-Husseini, A., El-Agroudy, A., Moustafa, F. et al. Impact of clinical and histopathological factors on outcome of egyptian patients with crescentic glomerulonephritis. Int Urol Nephrol 35, 543–551 (2003). https://doi.org/10.1023/B:UROL.0000025607.41722.aa

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  • DOI: https://doi.org/10.1023/B:UROL.0000025607.41722.aa

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