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New Quinoline Derivatives on the Basis of (4-Hydroxy-2-methylquinolin-3-yl)acetic Acid

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Abstract

A procedure was developed for the synthesis of (4-hydroxy-2-methylquinolin-3-yl)acetic acid and the corresponding acyl chloride. Reactions of the latter with o-aminobenzenethiol, o-phenylenediamine, o-aminophenol, anthranilic acid, and thiosemicarbazide gave, respectively, 2-(4-hydroxy-2-methylquinolin-3-ylmethyl)-1,3-benzothiazole, -benzoxazole, -benzimidazole, 2-(4-hydroxy-2-methylquinolin-3-ylmethyl)-4H-3,1-benzoxazin-4-one, and 4-hydroxy-2-methyl-3-(5-sulfanyl-1H-1,2,4-triazol-3-ylmethyl)quinoline.

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Authors and Affiliations

  1. Erevan State University, ul. A. Manukyana 1, Erevan, 375025, Armenia

    A. A. Avetisyan, I. L. Aleksanyan & A. A. Pivazyan

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  1. A. A. Avetisyan
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  2. I. L. Aleksanyan
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  3. A. A. Pivazyan
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Avetisyan, A.A., Aleksanyan, I.L. & Pivazyan, A.A. New Quinoline Derivatives on the Basis of (4-Hydroxy-2-methylquinolin-3-yl)acetic Acid. Russian Journal of Organic Chemistry 40, 889–891 (2004). https://doi.org/10.1023/B:RUJO.0000044555.03402.9b

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  • DOI: https://doi.org/10.1023/B:RUJO.0000044555.03402.9b

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