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Synthesis of 9,11-Ethano-13,15-isoxazolinoprostanoids, PGH Analogs

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Abstract

The 1,3-dipolar addition to terminal alkenes of nitrile oxides generated from nitromethylene derivatives of bicycloheptane provided 9,11-ethano-13,15-isoxazolinoprostanoids with alkyl, phenyl, or additional heterocyclic fragment in the ω-chain.

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Authors and Affiliations

  1. Institute of Bioorganic Chemistry, National Academy of Belarus, Minsk, 220141, Belarus

    N. F. Bondar', L. P. Isaenya, R. V. Skupskaya & F. A. Lakhvich

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  1. N. F. Bondar'
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  2. L. P. Isaenya
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  3. R. V. Skupskaya
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  4. F. A. Lakhvich
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Bondar', N.F., Isaenya, L.P., Skupskaya, R.V. et al. Synthesis of 9,11-Ethano-13,15-isoxazolinoprostanoids, PGH Analogs. Russian Journal of Organic Chemistry 39, 1089–1094 (2003). https://doi.org/10.1023/B:RUJO.0000010175.39145.9a

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  • DOI: https://doi.org/10.1023/B:RUJO.0000010175.39145.9a

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