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Sterilizing Effect of the Mutant Allele sbr 10 (l(1)ts403) in Compound with Null Allele in Drosophila melanogaster Females

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Abstract

In females of Df(1)v-L4/+(0/+) genotype, the presence of the wild-type allele ofsmall bristles (sbr) gene in a single dose has no significant effect on their fecundity, whereas a reduced dose of the temperature-sensitive allele sbr 10 (l(1)ts403) causes a strong sterilizing effect in females Df(1)v-L4/sbr 10 (0/sbr 10) at permissive temperature. We studied the contribution to this effects of the following factors: resorption of egg chambers, decreased oviposition, offspring death at the embryonic and larval stages, and reduced fecundity in females 0/sbr 10. Sterilizing effect of the mutant sbr 10 allele proved to be primarily caused by offspring lethality at the embryonic and first-instar larval stages. In 0/+ females, the majority of undeveloped eggs contained embryos that perished at the late developmental stages, whereas in females 0/sbr 10, at least 50% of undeveloped egg showed no visible signs of development or the embryo development was arrested at early stages of embryogenesis. The results obtained suggest insufficiency of the temperature-sensitive allele sbr 10 in haploid state to ensure the reproductive functions of Drosophila melanogaster females.

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Authors and Affiliations

  1. Department of Genetics and Breeding, St. Petersburg State University, St. Petersburg, 199034, Russia

    E. V. Golubkova, O. M. Pougatcheva, E. P. Demina, A. S. Musorina, A. N. Shershabova & L. A. Mamon

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  1. E. V. Golubkova
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  2. O. M. Pougatcheva
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  3. E. P. Demina
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  4. A. S. Musorina
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  5. A. N. Shershabova
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  6. L. A. Mamon
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Golubkova, E.V., Pougatcheva, O.M., Demina, E.P. et al. Sterilizing Effect of the Mutant Allele sbr 10 (l(1)ts403) in Compound with Null Allele in Drosophila melanogaster Females. Russian Journal of Genetics 40, 369–376 (2004). https://doi.org/10.1023/B:RUGE.0000024973.95306.b5

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