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Genetic and Molecular Characterization of New Natural Haplotype t wMP1 Found in House Mouse Mus domesticus R. from Peru

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Abstract

A new natural haplotype, t wMP1, found in a population of house mouse Mus domesticus from Peru, was subjected to genetic and molecular analyses. Experiments were performed to study the complementation of the new haplotype, fertility of t wMP1/t x heterozygotes, and transmission ratio distortion (TRD) of the t-carrying chromosome in the progeny of heterozygous males. Molecular analysis included blot hybridization with t-specific probes Tu48, Tu66, and Tu119. The results were collated with the structure and properties of the t complex, and the new haplotype was identified as a complete lethal one.

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Safronova, L.D., Shustrova, I.V. Genetic and Molecular Characterization of New Natural Haplotype t wMP1 Found in House Mouse Mus domesticus R. from Peru. Russian Journal of Genetics 39, 1240–1242 (2003). https://doi.org/10.1023/B:RUGE.0000004138.86664.f4

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  • DOI: https://doi.org/10.1023/B:RUGE.0000004138.86664.f4

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