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Acid-Base Properties of Some Penicillins

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Abstract

The acidity constants of benzylpenicillin, carbenicillin, and ampicillin were determined by pH-metric titration at 20°C and an ionic strength of 0.1 M (KCl). Diagrams of distribution of ionic and molecular forms of these compounds vs. pH were calculated.

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REFERENCES

  1. Navashin, S.M. and Fomina, I.P., Ratsional'naya antibiotikoterapiya (Rational Therapy with Antibiotics), Moscow: Meditsina, 1982.

    Google Scholar 

  2. Navashin, S.M. and Fomina, I.P., Polusinteticheskie penitsilliny (Semisynthetic Penicillins), Moscow: Meditsina, 1974.

    Google Scholar 

  3. Shemyakin, M.M. and Khokhlov, A.S., Khimiya antibioticheskikh veshchestv (Chemistry of Antibiotics), Moscow: GNTIKhL, 1953.

    Google Scholar 

  4. Preobrazhenskii, N.A. and Genkin, E.I., Khimiya organicheskikh lekarstvennykh veshchestv (Chemistry of Organic Medicines), Moscow: GNTIKhL, 1953.

    Google Scholar 

  5. Khimiya antibiotikov (Chemistry of Antibiotics), Shemyakin, M.M., Khokhlov, A.S., Kolosov, M.N., Bergel'son, L.D., and Antonov, V.K., Eds., Moscow: Akad. Nauk SSSR, 1961.

    Google Scholar 

  6. Sazykin, Yu.O., Antibiotiki kak ingibitory biokhimicheskikh protsessov (Antibiotics as Inhibitors of Biochemical Processes), Moscow: Nauka, 1968.

    Google Scholar 

  7. The Molecular Basis of Antibiotic Action, Gale, E.F., Ed., London: Wiley, 1972.

    Google Scholar 

  8. Franklin, T.J. and Snow, G.A., Biochemistry of Antimicrobial Action, London: Chapman and Hall, 1981, 3rd ed.

    Google Scholar 

  9. Inczédy, J., Analytical Applications of Complex Equilibria, Budapest: Akad. Kiadó, 1976.

    Google Scholar 

  10. Charykov, A.K. and Osipov, N.N., Karbonovye kisloty i karboksilatnye kompleksy v khimicheskom analize (Carboxylic Acids and Carboxylate Complexes in Chemical Analysis), Leningrad: Khimiya, 1991.

    Google Scholar 

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Authors and Affiliations

  1. Tver State University, Tver, Russia

    V. G. Alekseev & I. A. Volkova

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  1. V. G. Alekseev
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  2. I. A. Volkova
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Alekseev, V.G., Volkova, I.A. Acid-Base Properties of Some Penicillins. Russian Journal of General Chemistry 73, 1616–1618 (2003). https://doi.org/10.1023/B:RUGC.0000016033.20497.c9

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  • DOI: https://doi.org/10.1023/B:RUGC.0000016033.20497.c9

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