Abstract
It was shown in repeated experiments on 132 rats that proliferation in the corneal epithelium was nonspecifically enhanced after sialotomy. This effect appears to be due to the distant action of factors stimulating cell proliferation. The described phenomenon can be used for identification of mitogens formed during regeneration of the salivary glands.
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REFERENCES
Alov, I.A., Ocherki fiziologii mitoticheskogo deleniya kletok (Essays on Physiology of Mitotic Cell Division), Moscow: Meditsina, 1964.
Babaeva, A.G., Salivary Glands, Strukturnye osnovy adaptatsii i kompensatsii narushennykh funktsii (Structural Foundations of Adaptation and Compensation of Disturbed Functions), Sarkisov, D.S., <nt>Ed.</nt>, Moscow: Meditsina, 1987, pp. 185–194.
Babaeva, A.G. and Shubnikova, E.A., Struktura, funktsiya i adaptivnyi rost slyunnykh zhelez (Structure, Function, and Adaptive Growth of Salivary Glands), Moscow: Mosk. Gos. Univ., 1979.
Balasz, A. and Blaszek, I., Endogennye ingibitory kletochnoi proliferatsii (Endogenous Inhibitors of Cell Proliferation), Moscow: Mir, 1982.
Carlson, B.M., Regeneratsiya (Regeneration), Moscow: Nauka, 1986.
Denisov, A.B., Effects of Extracts from Normal and Burnt Skin on Cell Division in Corneal Epithelium, Byull. Eksp. Biol. Med., 1973, vol. 75, no. 5, pp. 93–96.
Denisov, A.B., Mitotic Index in Corneal Epithelium During Alteration of Tissues with Different Proliferative Activities, Byull. Eksp. Biol. Med., 1983, vol. 95, no. 3, pp. 88–89.
Denisov, A.B. and Mikhailov, V.V., On Formation of Regen-erative Stimulus after Trauma of Submaxillary Salivary Gland and Liver upon Total Inhibition of Sympathetic Ner-vous System, Byull. Eksp. Biol. Med., 1981, vol. 91, no. 3, pp. 364–365.
Devyatkov, N.D., Goland, M.B., and Rebrova, T.B., Radio-electronics and Medicine: On Possible Use of Certain Anal-ogies, Izv. Vyssh. Uchebn. Zaved., Radioelektronika, 1982, vol. 25, no. 9, pp. 3–8.
Glants, S., Mediko-Biologicheskaya Statistika (Statistics in Medicine and Biology), Moscow: Praktika, 1998.
Gusak, P.P., Mitotic Activity and Cell Composition of Aci-nuses in Regenerating Extraorbital Lacrymal Gland and Sub-maxillary Salivary Gland, Byull. Eksp. Biol. Med., 1980, vol.89, no. 7, pp. 99–101.
Konyshev, V.A., Stimulyatory i ingibitory rosta organov i tkanei zhivotnykh (Stimulators and Inhibitors of Growth of Animal Organs and Tissues), Moscow: Meditsina, 1974.
Konyshev, V.A., Transmission of Information In systems Regulating the Balance of Matter in the Organism, Uspekhi Fiziol. Nauk, 1980, vol. 11, no. 1, pp. 100–119.
Krasil'nikova, N.V., Diurnal Rhythm of Mitotic Activity in Mice under the Conditions of Altered Feeding Regime, Byull. Eksp. Biol. Med., 1962, vol. 54, no. 11, pp. 95–97.
Poradovskaya, T.P., On Pathway of Restoration of the Sub-maxillary Salivary Gland in Rats after Resection or Burn, Ontogenez, 1971, vol. 72, no. 6, pp. 586–590.
Ross, R., Vogel, A., Davies, R., and Rainer, E., The Platelet-Derived Growth Factor and Plasma Control Cell Prolifera-tion, Hormone and Cell Culture, New York: Cold Spring Harbor, 1979, pp. 3–16.
Serov, V.V. and Shekhter, A.B., Soedinitel'naya tkan' (Funkt-sional'naya morfologiya i obshchaya patologiya) (Connec-tive Tissue: Functional Morphology and General Pathology), Moscow: Meditsina, 1981.
Wissler, J.H., Inflammatory Mediators and Wound Hor-mones: Chemical Signals for Differentiation and Morpho-genesis in the Tissue Regeneration and Healing, Biochemi-cal. Differentiation and Morphogenesis, Berlin: Springer, 1982, pp. 257–274.
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Denisov, A.B. Development of a Model for the Role of Mitogens Initiating Repair Hyperplasia in Big Salivary Glands. Russian Journal of Developmental Biology 35, 288–291 (2004). https://doi.org/10.1023/B:RUDO.0000043822.58972.bc
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DOI: https://doi.org/10.1023/B:RUDO.0000043822.58972.bc