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Reaction of α,β-unsaturated trifluoromethyl ketones with cyclic enamines

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Abstract

The reactions of α,β-unsaturated trifluoromethyl ketones containing aromatic and heteroaromatic substituents with 1-morpholinocyclopentene, 1-morpholinocyclohexene, and 1-methyl-4-morpholino-1,2,5,6-tetrahydropyridine were studied. The reactions proceeded stereospecifically to give the corresponding bicyclo[3.2.1]octane, bicyclo[3.3.1]nonane, and azabicyclo[3.3.1]nonane derivatives.

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Nenajdenko, V.G., Druzhinin, S.V. & Balenkova, E.S. Reaction of α,β-unsaturated trifluoromethyl ketones with cyclic enamines. Russian Chemical Bulletin 53, 435–442 (2004). https://doi.org/10.1023/B:RUCB.0000030821.56661.44

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  • DOI: https://doi.org/10.1023/B:RUCB.0000030821.56661.44

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