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Plant Foods for Human Nutrition

, Volume 58, Issue 3, pp 1–7 | Cite as

Hypoglycemic potentials of methanolic extracts of selected plant foods in alloxanized mice

  • O.O. Ogundipe
  • J.O. Moody
  • T.O. Akinyemi
  • A. Raman
Article

Abstract

Crude methanolic extracts of five selected edible plant foods were tested for hypoglycemic activity in alloxanized mice. Fasting blood sugar levels were reduced significantly at differing rates. The order of their antidiabetic activity were H. sabdariffa, A. occidentalis, S. americanum, V. amygdalina, G. latifolium, H. sabdariffa, A. occidentalis and S. americanum, utilized at a dose of 100 mg/kg, had similar activity as chlorpropamide (5 mg/kg), which was used as a reference standard, in that they reduced blood sugar levels in mice below the initial values.

Alloxanized mice Hypoglycemic activity Plant foods 

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Copyright information

© Kluwer Academic Publishers 2003

Authors and Affiliations

  • O.O. Ogundipe
    • 1
  • J.O. Moody
    • 1
  • T.O. Akinyemi
    • 1
  • A. Raman
    • 2
  1. 1.Department of PharmacognosyFaculty of Pharmacy University of IbadanIbadanNigeria
  2. 2.Department of PharmacyKings CollegeLondonUK

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