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Pharmaceutical Prospects for RNA Interference

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Abstract

RNA interference has proven to be a powerful tool in gene function validation. Recently, the first studies were published reporting a disease-modulating activity of the technique, suggesting a promise for RNA interference as a novel therapeutic strategy. This review discusses the recent advancements in realizing the clinical utility of RNA-interference.

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Authors and Affiliations

  1. Department of Pharmaceutics, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, PO Box 80082, 3508 TB, Utrecht, The Netherlands

    Raymond M. Schiffelers

  2. Intradigm Corporation, 12115K Parklawn Drive, Rockville, Maryland, 20852

    Martin C. Woodle & Puthupparampil Scaria

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  1. Raymond M. Schiffelers
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Correspondence to Raymond M. Schiffelers.

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Schiffelers, R.M., Woodle, M.C. & Scaria, P. Pharmaceutical Prospects for RNA Interference. Pharm Res 21, 1–7 (2004). https://doi.org/10.1023/B:PHAM.0000012145.49054.6c

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