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Synthesis, Structure, and Biological Activity of Acylpyruvic Acids and Related 2-Imino Derivatives (A Review)

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REFERENCES

  1. V. I. Saloutin, Ya. V. Burgart, and O. N. Chupakhin, Usp. Khim., 68(3), 227–239 (1999).

    Google Scholar 

  2. V. I. Saloutin, Ya. V. Burgart, C. O. Kappe, et al., Heterocycles, 52, 1411–1434 (2000).

    Google Scholar 

  3. S. G. Perevalov, Ya. V. Burgart, V. I. Saloutin, et al., Usp. Khim., 70(11), 1039–1058 (2001).

    Google Scholar 

  4. V. O. Koz'minykh and E. N. Koz'minykh, in: Selected Methods for the Synthesis and Modification of Heterocycles, V. G. Kartsev (ed.), IBS Press, Moscow (2002), Vol. 1, pp. 264–280.

    Google Scholar 

  5. V. O. Koz'minykh, and E. N. Koz'minykh, in: Pharmaceutical Science and Education: Current Problems, Advances, and Prospects (Abstracts of Papers. The Interinstitution Sci.-Pract. Conf. “Higher Education Contributing to the Urals Region”) [in Russian], Perm State Pharmaceutical Academy, Perm (2002), pp. 25–26.

    Google Scholar 

  6. S. N. Shurov and Yu. S. Andreichikov, in: The Chemistry of Five-Member 2,3-Dioxoheterocycles [in Russian], Perm State Univ., Perm (1994), pp. 5–54.

    Google Scholar 

  7. G. Kollenz, in: The Chemistry of Five-Member 2,3-Dioxoheterocycles [in Russian], Perm State Univ., Perm (1994), pp. 55–73.

    Google Scholar 

  8. D. D. Nekrasov, Khim. Geterotsikl. Soedin., No. 3, 291–304 (2001).

    Google Scholar 

  9. D. D. Nekrasov, in: The History of Chemistry: A Field of Science and Subject of Education (On the 100 Anniversary of Prof. N. A. Figurovskii) [in Russian], Moscow State Univ., Moscow (2001), pp. 133–141.

    Google Scholar 

  10. A. N. Maslivets and Yu. S. Andreichikov, in: The Chemistry of Five-Member 2,3-Dioxoheterocycles [in Russian], Perm State Univ., Perm (1994), pp. 91–122.

    Google Scholar 

  11. E. V. Pimenova and Yu. S. Andreichikov, in: The Chemistry of Five-Member 2,3-Dioxoheterocycles [in Russian], Perm State Univ., Perm (1994), pp. 188–204.

    Google Scholar 

  12. C. Beyer and L. Claisen, Ber., 20, 2184–2188 (1887).

    Google Scholar 

  13. E. Brömme and L. Claisen, Ber., 21, 1131–1135 (1888).

    Google Scholar 

  14. Beilstein Handbuch der Organischen Chemie, Berlin (1921), Vol. 3E, p. 747; (1927), Vol. 10E, p. 814, 815; (1929), Vol. 3–4E, p. 261; (1942), Vol. 3–4E, p. 465; (1962), Vol. 3E, p. 1331; (1972), Vol. 10E, p. 3546.

  15. M. Laćan and V. Rapiš, Croat. Chem. Acta, 42(3), 411–416 (1970).

    Google Scholar 

  16. M. Laćcan and R. Šarac-Arneri, Croat. Chem. Acta, 43(4), 215–219 (1971).

    Google Scholar 

  17. B. P. Clark, W. J. Ross, and A. Todd, UK Patent Application No. 2 123 813 (1984).

  18. Yu. S. Andreichikov, Methods for the Synthesis of Biologically Active Heterocyclic Compounds [in Russian], Perm State Univ., Perm (1989), pp. 1–23.

    Google Scholar 

  19. O. V. Parfenov, S. A. Artem'ev, and V. Kh. Khamaev, Proceedings of the Regional Meeting of the Republics of Middle Asia and Kazakhstan “Chemical Reagents” [in Russian], Tashkent (1990), Vol. 1, Part 2, p. 292.

    Google Scholar 

  20. M. Stiles and J. P. Selegue, J. Org. Chem., 56(12), 4067–4070 (1991).

    Google Scholar 

  21. I. B. Podvintsev, S. N. Shurov, and Yu. S. Andreichikov, Deposited at VINITI (24.09.97), No. 2906-B, Perm (1997), pp. 1–14.

    Google Scholar 

  22. S. N. Shurov, I. B. Podvintsev, L. S. Kosvintseva, et al., Zh. Org. Khim., 33(8), 1192–1200 (1997).

    Google Scholar 

  23. I. B. Podvintsev, Author's Abstract of Cand. Sci. (Chem.) Thesis [in Russian], Perm State Univ., Perm (1997).

    Google Scholar 

  24. T. N. Yanborisov, I. A. Zhikina, Yu. S. Andreichikov, et al., Khim.-Farm. Zh., 32(9), 26–28 (1998).

    Google Scholar 

  25. E. N. Koz'minykh, Author's Abstract of Doctoral (Pharm. Sci.) Thesis [in Russian], Perm (1999).

  26. V. O. Koz'minykh, N. M. Igidov, E. S. Berezina, et al., Izv. Akad. Ross Nauk, Ser. Khim., No. 9, 1564–1568 (2000).

    Google Scholar 

  27. E. S. Berezina, V. O. Koz'minykh, N. M. Igidov, et al., Zh. Org. Khim., 37(4), 574–581 (2001).

    Google Scholar 

  28. O. A. Sof'ina, N. M. Igidov, E. N. Koz'minykh, et al., Zh. Org. Khim., 37(7), 1067–1075 (2001).

    Google Scholar 

  29. H. A. Burch and J. E. Gray, J. Med. Chem., 15(4), 429–431 (1972).

    Google Scholar 

  30. L. Brecker, M. Pogorevc, H. Griengl, et al., New J. Chem., 234(4), 437–446 (1999); Chem. Abstr., 131, 58630v (1999).

    Google Scholar 

  31. D. Pokorny, L. Brecker, M. Pogorevc, et al., J. Bacteriol., 181(16), 5051–5059 (1999); Chem. Abstr., 131, 296961y (1999).

    Google Scholar 

  32. G. N. Walker, US Patent No. 3449350 (1969).

  33. C. E. Mounier, J. Shi, S. R. Sirimanne, et al., J. Biol. Chem., 272(8), 5016–5023 (1997).

    Google Scholar 

  34. O. Mumm and H. Hornhardt, Ber., 70B(9), 1930–1947 (1937).

    Google Scholar 

  35. A. Meister and J. P. Greenstein, J. Biol. Chem., 175, 573–588 (1948); Chem. Abstr., 43, 705g (1949).

    Google Scholar 

  36. R. G. Cooke, B. K. Merrett, G. J. O'Loughlin, et al., Austral. J. Chem., 33(10), 2317–2324 (1980).

    Google Scholar 

  37. V. A. Zagorevskii and D. A. Zykov, Zh. Obsch. Khim., 33(8), 2469–2471 (1963).

    Google Scholar 

  38. I. I. Lapkin and Yu. S. Andreichikov, Zh. Org. Khim., 2(3), 388–390 (1966).

    Google Scholar 

  39. L. I. Vereshchagin, L. D. Gavrilov, R. L. Bol'shedvorskaya, et al., Zh. Org. Khim., 10(10), 2059–2064 (1974).

    Google Scholar 

  40. A. P. Kozlov, L. A. Perevozchikov, and S. A. Perevozchikova, Abstracts of Papers. The 3rd Urals Conf. “Enamines in Organic Synthesis” [in Russian], Perm State Techn. Univ., Perm (1999), p. 21.

    Google Scholar 

  41. A. P. Kozlov, L. A. Perevozchikov, and S. A. Perevozchikova, in: Pharmaceutical Science and Education: Current Problems, Advances, and Prospects (Abstracts of Papers. The Interinstitution Sci.-Pract. Conf.) [in Russian], Perm State Pharmaceutical Academy, Perm (2000), pp. 49–50.

    Google Scholar 

  42. S. A. Perevozchikova, L. A. Perevozchikov, and A. P. Kozlov, in: Prospects of Development of Natural Sciences in Universities (Proc. Intern. Sci. Conf.) [in Russian], Perm State Univ., Perm (2001), Vol. 1, pp. 88–90.

    Google Scholar 

  43. Yu. S. Andreichikov, S. P. Tendryakova, Yu. A. Nalimova, et al., USSR Inventor's Certificate No. 740747 (1980); Otkrytiya, No. 22, 140 (1980).

    Google Scholar 

  44. G. Kollenz, C. O. Kappe, and H. A. Nabey, Heterocycles, 32(4), 669–673 (1991).

    Google Scholar 

  45. A. O. Belyaev, E. N. Koz'minykh, and V. O. Koz'minykh, in: Pharmaceutical Science and Education: Current Problems, Advances and Prospects (Abstracts of Papers. The Jubilee Interinstitution Sci.-Pract. Conf. “85 Years of High Education in the Urals Region”) [in Russian], Perm (2001), p. 32.

  46. A. O. Belyaev, E. N. Koz'minykh, and V. O. Koz'minykh, in: Pharmaceutical Science and Education: Current Problems, Advances, and Prospects (Abstracts of Papers. The Interinstitution Sci.-Pract. Conf. “Higher Education Contributing to the Urals Region”) [in Russian], Perm State Pharmaceutical Academy, Perm (2002), p. 109.

    Google Scholar 

  47. A. O. Belyaev, V. V. Novikova, E. N. Koz'minykh, et al., in: Clinical Investigations of Drugs (Proc. 2nd Intern. Conf.) [in Russian], Svyatygor, Moscow (2002), pp. 30–31.

    Google Scholar 

  48. A. O. Belyaev, E. N. Koz'minykh, and V. O. Koz'minykh, Bashkir. Khim. Zh., 9(3), 47–48 (2002).

    Google Scholar 

  49. Yu. S. Andreichikov, N. V. Gel't, and A. P. Kozlov, Zh. Org. Khim., 20(8), 1749–1755 (1984).

    Google Scholar 

  50. E. N. Koz'minykh, N. M. Igidov, and V. O. Koz'minykh, in: 80 Years of Pharmaceutical Education in Urals Region: Advances and Prospects (Abstracts of Papers. The Jubilee Interinstitution Sci.-Pract. Conf.) [in Russian], Perm State Techn. Univ., Perm (1998), pp. 54–55.

    Google Scholar 

  51. T. M. Shironina, O. A. Sof'ina, E. N. Koz'minykh, et al., in: Modern Science Contributing to Agriculture of Near-Kama Region (Abstracts of Papers. The 57th Interinstitution Conf. Devoted to 80 Years of Agricultural Education and Science in the Urals Region) [in Russian], Perm State Agricultural Academy, Perm (1998), Issue 3, p. 25.

    Google Scholar 

  52. E. N. Koz'minykh, N. M. Igidov, N. V. Kolotova, et al., in: Chemistry for Medicine and Veterinary (A Collection of Scientific Works) [in Russian], Saratov State Univ., Saratov (1998), pp. 90–93.

    Google Scholar 

  53. S. S. Kataev, Author's Abstract of Cand. Sci. (Chem.) Thesis [in Russian], Perm State Univ., Perm (1999).

    Google Scholar 

  54. E. N. Koz'minykh, E. A. Chupilova, N. M. Igidov, et al., in: Pharmaceutical Science and Education: Current Problems, Advances, and Prospects (Abstracts of Papers. The Interinstitution Sci.-Pract. Conf.) [in Russian], Perm State Pharmaceutical Academy, Perm (2000), pp. 59–60.

    Google Scholar 

  55. Z. G. Aliev, S. N. Shurov, D. D. Nekrasov, et al., Zh. Strukt. Khim., 41(6), 1255–1260 (2000).

    Google Scholar 

  56. W. Irowitzsch and H. Sahm, FRG Patent Application No. 2705881 (1978).

  57. N. M. Igidov, O. A. Sof'ina, T. M. Shironina, et al., in: Organic Synthesis and Combinatory Chemistry (Abstracts of Papers. Intern. Sci. Conf.) [in Russian], Moscow (1999), p. 106.

  58. S. S. Shirinkina, Yu. S. Kasatkina, V. O. Koz'minykh, et al., in: Pharmaceutical Science and Education: Current Problems, Advances and Prospects (Abstracts of Papers. The Interinstitution Sci.-Pract. Conf.) [in Russian], Perm (2000), pp. 83–84.

  59. S. S. Shirinkina, N. M. Igidov, E. S. Berezina, et al., in: Pharmaceutical Science and Education: Current Problems, Advances and Prospects (Abstracts of Papers. The Jubilee Interinstitution Sci.-Pract. Conf. “85 Years of High Education in the Urals Region”) [in Russian], Perm (2001), pp. 70–71.

  60. S. S. Shirinkina, N. M. Igidov, E. S. Berezina, et al., in: Student's Science Contributing to Solving Developmental Problems of Near-Kama Region (Abstracts of Papers. The 58–59th Interinstitution Conf.) [in Russian], Perm State Agricultural Academy, Perm (2001), Issue 5, pp. 9–10.

    Google Scholar 

  61. S. S. Shirinkina, N. M. Igidov, E. S. Berezina, et al., in: Prospects of Development of Natural Sciences in Universities (Proc. Intern. Sci. Conf.) [in Russian], Perm State Univ., Perm (2001), Vol. 1, pp. 150–152.

    Google Scholar 

  62. S. S. Zykova, Author's Abstract of Cand. Sci. (Pharm.) Thesis [in Russian], Perm (2002).

  63. Beilstein Handbuch der Organischen Chemie, Berlin (1921), Vol. 10, p. 567.

  64. J. P. Guthrie, J. Am. Chem Soc., 94(24), 7020–7024 (1972).

    Google Scholar 

  65. P. Battesti, O. Battesti, and M. Sélim, Bull. Soc. Chim. Fr., No. 9–10, 2214–2220 (1974).

    Google Scholar 

  66. A. P. Kozlov, V. V. Ryabova, G. A. Kozlova, et al., Zh. Org. Khim., 33(3), 413–417 (1997).

    Google Scholar 

  67. Yu. S. Andreichikov, R. F. Saraeva, Yu. A. Nalimova, et al., Zh. Org. Khim., 14(2), 371–373 (1978).

    Google Scholar 

  68. Yu. S. Andreichikov, A. P. Kozlov, and L. A. Voronova, Zh. Org. Khim., 14(12), 2559–2564 (1978).

    Google Scholar 

  69. Yu. S. Andreichikov, S. P. Tendryakova, Yu. A. Nalimova, et al., Zh. Org. Khim., 18(1), 193–198 (1982).

    Google Scholar 

  70. N. N. Shapet'ko, S. A. Khatipov, Yu. S. Andreichikov, et al., Zh. Obshch. Khim., 55(3), 661–667 (1985).

    Google Scholar 

  71. A. P. Kozlov, V. V. Ryabova, and Yu. S. Andreichikov, Zh. Org. Khim., 23(8), 1665–1670 (1987).

    Google Scholar 

  72. A. P. Kozlov, V. V. Ryabova, G. A. Kozlova, et al., Zh. Org. Khim., 33(3), 406–412 (1997).

    Google Scholar 

  73. N. V. Kolotova, V. O. Koz'minykh, É. V. Dolbilkina, et al., Izv. Ross Akad. Nauk, Ser. Khim., No. 11, 2317–2319 (1998).

    Google Scholar 

  74. N. V. Kolotova, V. O. Koz'minykh, É. V. Dolbilkina, et al., Khim.-Farm. Zh., 32(9), 32–35 (1998).

    Google Scholar 

  75. E. N. Koz'minykh, A. O. Belyaev, and V. O. Koz'minykh, Bashkir. Khim. Zh., 9(4), 35–37 (2002).

    Google Scholar 

  76. E. N. Koz'minykh, A. O. Belyaev, V. O. Koz'minykh, et al., Khim.-Farm. Zh., 36(11), 28–30 (2002).

    Google Scholar 

  77. A. E. Rubtsov, R. R. Makhmudov, N. V. Kovylyaeva, et al., Khim.-Farm. Zh., 36(11), 31–35 (2002).

    Google Scholar 

  78. A. P. Kozlov and V. V. Ryabova, in: Nucleophilic Reactions of Carbonyl Compounds (Abstracts of Papers of the 3rd Interinstitution Conf.) [in Russian], Saratov State Univ., Saratov (1985), p. 65.

    Google Scholar 

  79. R. F. Saraeva, Author's Abstract of Cand. Sci. (Chem.) Thesis [in Russian], Perm State Univ., Perm (1973).

    Google Scholar 

  80. A. P. Kozlov, V. V. Ryabova, and L. I. Varkentin, in: the Chemistry of Unsaturated Compounds (Abstract of Papers of the All-Union Conf. devoted to the Memory of A. M. Butlerov) [in Russian], Kazan (1986), Part 2, p. 120.

  81. A. P. Kozlov, V. V. Ryabova, and Yu. S. Andreichikov, in: Mechanisms of Nucleophilic Substitution and Addition Reactions (Abstracts of the All-Union Meeting) [in Russian], Donetsk (1991), p. 119.

  82. A. P. Kozlov, Author's Abstract of Doctoral (Chem. Sci.) Thesis [in Russian], Saratov (1996).

  83. A. E. Rubtsov and V. V. Zalesov, in: Pharmaceutical Science and Education: Current Problems, Advances and Prospects (Abstracts of Papers. The Jubilee Interinstitution Sci.-Pract. Conf. “85 Years of High Education in the Urals Region”) [in Russian], Perm (2001), p. 57.

  84. A. E. Rubtsov, N. V. Kovylyaeva, and V. V. Zalesov, The Chemistry and Biological Activity of Nitrogen-Containing Heterocycles and Alkaloids (Proc. 1st Intern. Conf.) [in Russian], Iridium Press, Moscow (2001), Vol. 2, p. 257.

    Google Scholar 

  85. A. O. Belyaev, R. R. Makhmudov, V. V. Novikova, et al., in: Chemistry in Technology and Medicine (Proc. All-Russia Sci.-Pract. Conf.) [in Russian], Dagestan State Univ., Makhachkala (2002), pp. 94–96.

    Google Scholar 

  86. E. N. Koz'minykh, A. O. Belyaev, and V. O. Koz'minykh, in: Pharmaceutical Science and Education: Current Problems, Advances, and Prospects (Abstracts of Papers. The Interinstitution Sci.-Pract. Conf. “Higher Education Contributing to the Urals Region”) [in Russian], Perm State Pharmaceutical Academy, Perm (2002), p. 112.

    Google Scholar 

  87. A. O. Belyaev, E. N. Koz'minykh, and V. O. Koz'minykh, Bashkir. Khim. Zh., 9(4), 33–35 (2002).

    Google Scholar 

  88. E. N. Koz'minykh, A. O. Belyaev, V. O. Koz'minykh, et al., Khim.-Farm. Zh., 37(2), 21–24 (2003).

    Google Scholar 

  89. V. I. Saloutin, I. T. Bazyl', Z. É. Skryabina, et al., Izv. Ross. Akad. Nauk, Ser. Khim., No. 2, 299–302 (1994).

    Google Scholar 

  90. V. I. Saloutin, Z. E. Skryabina, I. T. Bazyl', et al., J. Fluor. Chem., 69(1), 119–126 (1994).

    Google Scholar 

  91. A. E. Rubtsov, R. R. Makhmudov, and V. V. Zalesov, Abstracts of Papers. Young Scientist Workshop on Organic Chemistry [in Russian], Urals Div., Russ. Acad. Sci., Yekaterinburg (2000), p. 201.

    Google Scholar 

  92. A. E. Rubtsov, R. R. Makhmudov, N. V. Kovylyaeva, et al., in: Prospects of Development of Natural Sciences in Universities (Proc. Intern. Sci. Conf.) [in Russian], Perm State Univ., Perm (2001), Vol. 1, pp. 171–175.

    Google Scholar 

  93. A. E. Rubtsov and V. V. Zalesov, Khim. Geterotsikl. Soedin., No. 8, 1130–1134 (2001).

    Google Scholar 

  94. A. O. Belyaev, R. R. Makhmudov, E. N. Koz'minykh, et al., in: Pharmaceutical Science and Education: Current Problems, Advances, and Prospects (Abstracts of Papers. The Interinstitution Sci.-Pract. Conf. “Higher Education Contributing to the Urals Region”) [in Russian], Perm State Pharmaceutical Academy, Perm (2002), p. 14.

    Google Scholar 

  95. Yu. S. Andreichikov, R. F. Saraeva, Yu. A. Nalimova, et al., USSR Inventor's Certificate No. 488 811 (1975); Otkrytiya, No. 39, 64 (1975).

    Google Scholar 

  96. N. V. Kovylyaeva, R. R. Makhmudov, and V. V. Zalesov, in: Prospects of Development of Natural Sciences in Universities (Proc. Intern. Sci. Conf.) [in Russian], Perm State Univ., Perm (2001), Vol. 1, p. 214.

    Google Scholar 

  97. N. V. Kovylyaeva, R. R. Makhmudov, S. S. Kataev, et al., in: Current Problems in Organic Chemistry (Abstracts of Papers of Young Scientist Workshop-Conf.) [in Russian], Urals Div., Russ. Acad. Sci., Yekaterinburg (2000), p. 139.

    Google Scholar 

  98. O. Mumm and C. Bergell, Ber., 45, 3046–3051 (1912).

    Google Scholar 

  99. W. Küster and E. Erfle, Ber., 59, 1015–1022 (1926).

    Google Scholar 

  100. Yu. S. Andreichikov, T. N. Tokmakova, and L. A. Voronova, et al., Zh. Org. Khim., 12(5), 1073–1076 (1976).

    Google Scholar 

  101. O. A. Sof'ina, V. O. Koz'minykh, N. M. Igidov, et al., in: Pharmaceutical Science and Education: Current Problems, Advances and Prospects (Abstracts of Papers. The Interinstitution Sci.-Pract. Conf.) [in Russian], Perm (2000), pp. 73–74.

  102. O. A. Sof'ina, V. O. Koz'minykh, N. M. Igidov, et al., in: Organic Chemistry in 20th Century (Abstracts of Papers. The Young Scientist Workshop) [in Russian], Moscow (2000), p. 110.

  103. E. N. Koz'minykh, N. V. Kolotova, N. M. Igidov, et al., in: Carbonyl compounds in the Synthesis of Heterocycles (A Collection of Scientific Works) [in Russian], Saratov State Univ., Saratov (1996), p. 128.

    Google Scholar 

  104. N. V. Kolotova and V. O. Koz'minykh, in: Prospects of Development of Natural Sciences in Western Urals (Proc. Intern. Sci. Conf.) [in Russian], Perm State Univ., Perm (1996), Vol. 1, pp. 37–38.

    Google Scholar 

  105. N. V. Kolotova, E. N. Koz'minykh, G. N. Novoselova, et al., in: Pharmaceutical Science and Practice under New Social-Economic Conditions (A Collection of Scientific Works of the Research Institute of Pharmacy) [in Russian], Moscow (1997), Vol. 36, Part 2, pp. 8–12.

    Google Scholar 

  106. A. N. Maslivets, L. I. Smirnova, O. I. Ivanenko, et al., Khim. Geterotsikl. Soedin., No. 5, 697 (1991).

    Google Scholar 

  107. S. Salvatori, Gazz. Chim. Ital., 21(2), 286–291 (1891).

    Google Scholar 

  108. T. M. Shironina, E. N. Koz'minykh, N. M. Igidov, et al., in: Pharmaceutical Science and Practice (Abstracts of Papers. Sci.-Pract. Conf.) [in Russian], Kemerovo State Med. Acad., Kemerovo (1999), pp. 164–165.

    Google Scholar 

  109. T. M. Shironina, E. N. Koz'minykh, N. M. Igidov, et al., in: Pharmaceutical Science and Education: Current Problems, Advances and Prospects (Abstracts of Papers. The Interinstitution Sci.-Pract. Conf.) [in Russian], Perm (2000), p. 85.

  110. T. M. Shironina, E. N. Koz'minykh, E. S. Berezina, et al., in: Organic Chemistry in the 20th Century (Abstracts of Papers. The Young Scientist Workshop) [in Russian], Moscow (2000), p. 106.

  111. T. M. Shironina, E. N. Koz'minykh, N. M. Igidov, et al., Deposited at VINITI (15.05.01), No. 1252–B2001, Perm (2001), pp. 1–12.

    Google Scholar 

  112. T. M. Shironina, E. N. Koz'minykh, N. M. Igidov, et al., in: Prospects of Development of Natural Sciences in Universities (Proc. Intern. Sci. Conf.) [in Russian], Perm State Univ., Perm (2001), Vol. 1, pp. 145–149.

    Google Scholar 

  113. T. M. Shironina, E. N. Koz'minykh, N. M. Igidov, et al., in: Current Problems in the Chemistry and Ecology (Proc. Reg. Sci. Conf.) [in Russian], Perm State Techn. Univ., Perm (2001), pp. 22–23.

    Google Scholar 

  114. T. M. Shironina, Author's Abstract of Cand. Sci. (Pharm.) Thesis [in Russian], Perm (2002).

  115. N. M. Igidov, T. M. Shironina, E. N. Koz'minykh, et al., in: Pharmaceutical Science and Education: Current Problems, Advances and Prospects (Abstracts of Papers. The Interinstitution Sci.-Pract. Conf.) [in Russian], Perm (2000), p. 45.

  116. Yu. S. Kasatkina, N. M. Igidov, T. M. Shironina, et al., in: Current Problems in Theoretical and Experimental Analytical Chemistry (Proc. Reg. Sci. Conf.) [in Russian], Perm State Univ., Perm (2002), p. 111.

    Google Scholar 

  117. A. V. Milyutin, N. M. Igidov, E. N. Koz'minykh, et al., in: Pharmaceutical Science and Education: Current Problems, Advances and Prospects (Abstracts of Papers. The Interinstitution Sci.-Pract. Conf.) [in Russian], Perm (2000), pp. 65–67.

  118. T. M. Shironina, E. N. Koz'minykh, N. M. Igidov, et al., in: Current Problems in Organic Chemistry (Proc. Sci. Workshop-Conf., 2–6 April 2001, Novosibirsk) [in Russian], Yekaterinburg (2001), pp. 327–328.

  119. A. E. Korzun, in: Current Problems in Theoretical and Experimental Chemistry (Proc. 8th All-Russia Stud. Sci. Conf.) [in Russian], Urals State Univ., Yekaterinburg (1998), pp. 110–111.

    Google Scholar 

  120. E. A. Glebova, N. A. Pulina, S. S. Kataev, et al., Abstracts of Papers. Young Scientist Workshop on Organic Chemistry [in Russian], Urals State Univ., Yekaterinburg (2000), p. 199.

    Google Scholar 

  121. L. N. Kurkovskaya, N. N. Shapet'ko, Yu. S. Andreichikov, et al., Zh. Strukt. Khim., 16(1), 139–141 (1975).

    Google Scholar 

  122. L. N. Kurkovskaya, N. N. Shapet'ko, Yu. S. Andreichikov, et al., Zh. Strukt. Khim., 13(6), 1026–1032 (1972).

    Google Scholar 

  123. S. I. Yakimovich, I. V. Zerova, and N. N. Gavrilova, Zh. Org. Khim., 13(2), 263–271 (1977).

    Google Scholar 

  124. S. I. Yakimovich and I. V. Zerova, Zh. Org. Khim., 14(1), 42–48 (1978).

    Google Scholar 

  125. S. I. Yakimovich, I. V. Zerova, and K. B. Pumpor, Abstracts of Papers. the 1st All-Russia Conf. on the Chemistry of Heterocycles [in Russian], Contact-Service Publ., Suzdal (2000), p. 507.

    Google Scholar 

  126. S. Yu. Solodnikov, H. D. Miles, O. P. Krasnykh, et al., Khim.-Farm. Zh., 36(5), 10–11 (2002).

    Google Scholar 

  127. N. E. Gavrilova, E. A. Glebova, V. V. Zalesov, et al., in: Current Problems in Development, Production, and Use of Immunobiological and Pharmaceutical Preparations (Proc. All-Russia Sci. Conf.) [in Russian], Immunopreparat, Ufa (2000), Part 2, pp. 48–51.

    Google Scholar 

  128. R. R. Makhmudov, in: Prospects of Development of Natural Sciences in Universities (Proc. Intern. Sci. Conf.) [in Russian], Perm State Univ., Perm (2001), Vol. 1, pp. 158–162.

    Google Scholar 

  129. N. N. Trapeznikova, Author's Abstract of Cand. Sci. (Chem.) Thesis [in Russian], Perm State Pharmaceutical Academy, Perm (2002).

    Google Scholar 

  130. A. O. Belyaev, E. N. Koz'minykh, V. O. Koz'minykh, et al., in: Pharmaceutical Science and Education: Current Problems, Advances, and Prospects (Abstracts of Papers. The Interinstitution Sci.-Pract. Conf. “Higher Education Contributing to the Urals Region”) [in Russian], Perm State Pharmaceutical Academy, Perm (2002), p. 13.

    Google Scholar 

  131. A. O. Belyaev, V. V. Novikova, E. N. Koz'minykh, et al., in: Pharmaceutical Science and Education: Current Problems, Advances, and Prospects (Abstracts of Papers. The Interinstitution Sci.-Pract. Conf. “Higher Education Contributing to the Urals Region”) [in Russian], Perm State Pharmaceutical Academy, Perm (2002), p. 110.

    Google Scholar 

  132. A. O. Belyaev, E. N. Koz'minykh, E. S. Berezina, et al., in: Abstracts of Papers. The 67th Interinstitution Sci. Conf. of Students and Young Scientists) [in Russian], Kursk State Medical Univ., Kursk (2002), p. 100.

    Google Scholar 

  133. A. O. Belyaev, E. N. Koz'minykh, V. O. Koz'minykh, in: Science of Humans (A Coll. of Papers of the 3rd Congr. of Young Scientists and Specialists) [in Russian], Siberian State Medical University, Tomsk (2002), p. 203.

    Google Scholar 

  134. Yu. S. Andreichikov, G. D. Plakhina, S. G. Pitirimova, et al., Khim.-Farm. Zh., 12(1), 76–78 (1978).

    Google Scholar 

  135. E. N. Koz'minykh, A. O. Belyaev, E. S. Berezina, et al., Khim.-Farm. Zh., 36(12), 9–11 (2002).

    Google Scholar 

  136. N. M. Igidov, E. N. Koz'minykh, A. V. Milyutin, et al., Khim.-Farm. Zh., 30(11), 21–25 (1996).

    Google Scholar 

  137. E. N. Koz'minykh, N. M. Igidov, E. S. Berezina, et al., Khim.-Farm. Zh., 30(7), 31–35 (1996).

    Google Scholar 

  138. A. V. Milyutin, L. R. Amirova, I. V. Krylova, et al., Khim.-Farm. Zh., 31(1), 32–35 (1997).

    Google Scholar 

  139. A. O. Belyaev, A. V. Zakhmatov, E. N. Koz'minykh,, et al., in: Abstracts of Papers. The Near-Kama Reg. Sci. Conf. of Students, Post-Graduates and Young Scientists [in Russian], Perm State Techn. Univ., Perm (2002), p. 142.

    Google Scholar 

  140. A. O. Belyaev, A. V. Zakhmatov, E. N. Koz'minykh,, et al., in: Chemistry in Technology and Medicine (Proc. All-Russia Sci.-Pract. Conf.) [in Russian], Dagestan State Univ., Makhachkala (2002), pp. 96–98.

    Google Scholar 

  141. H. W. R. Williams, E. Eichler, W. C. Randall, et al., J. Med. Chem., 26(8), 1196–1200 (1983).

    Google Scholar 

  142. E. J. Cragoe, A. A. Patchett, C. S. Rooney, and H. W. R. Williams, US Patent No. 4336397 (1982).

  143. C. S. Rooney and H. W. R. Williams, US Patent No. 4337258 (1982).

  144. C. S. Rooney and H. W. R. Williams, US Patent No. 4423063 (1983).

  145. J. E. Tomassini, H. G. Selnick, M. E. Davis, et al., Antimicrob. Agents Chemother., 38(12), 2827–2837 (1994).

    Google Scholar 

  146. H. G. Selnick, G. S. Ponticello, J. J. Baldwin, and J. E. Tomassini, US Patent No. 5475109 (1995).

  147. J. C. Hastings, H. G. Selnick, B. Wolanski, and J. E. Tomassini, Antimicrob. Agents Chemother., 40(5), 1304–1307 (1996).

    Google Scholar 

  148. H. G. Selnick, J. J. Baldwin, G. S. Ponticello, and J. E. Tomassini, US Patent No. 5618830 (1997).

  149. J. L. Cole, L. C. Kuo, and D. B. Olsen, US Patent No. 5660989 (1997).

  150. T. Fujishita and T. Yoshinaga, US Patent No. 6333323 (2001).

  151. T. Fujishita and T. Yoshinaga, US Patent No. 6506787 (2003).

  152. Sergio, L. Tomei, U. Koch, et al., US Patent No. 6492423 (2002).

  153. J. S. Wai, M. S. Egbertson, L. S. Payne, et al., J. Med. Chem., 43(26), 4923–4926 (2000).

    Google Scholar 

  154. S. D. Young, J. S. Way, M. W. Embrey, et al., US Patent No. 6262055 (2001).

  155. H. G. Selnick, M. S. Egbertson, D. J. Hazuda, et al., US Patent No. 6306891 (2001).

  156. G. C. Pais, X. Zhang, C. Marchand, et al., J. Med. Chem., 45(15), 3184–3194 (2002).

    Google Scholar 

  157. S. D. Young, M. S. Egbertson, L. S. Payne, et al., US Patent No. 6380249 (2002).

  158. E. De Clercq, Biochim. Biophys. Acta, 1587, 258–275 (2002).

    Google Scholar 

  159. E. De Clercq, Med. Res. Rev., 22(6), 531–565 (2002).

    Google Scholar 

  160. M. A. Walker, T. D. Johnson, O. K. Kim, et al., US Patent No. 6548546 (2003).

  161. C. A. Shaw-Reid, V. Munshi, P. Graham, et al., J. Biol. Chem., 278(5), 2777–2780 (2003).

    Google Scholar 

  162. P. C. Astles, M. F. Harper, N. V. Harris, et al., US Patent No. 6211234 (2001).

  163. H. Miles, S. Yu. Solodnikov, O. P. Krasnykh, et al., US Patent No. 6602907 (2003).

  164. A. V. Zakhmatov, A. Yu. Borodin, A. A. Povol'skikh, et al., in: Current Problems in theoretical and Practical Medicine (Proc. 68th Rep. Sci.-Pract. Conf.) [in Russian], Bashkir State Med. Univ., Ufa (2003), pp. 150–151.

    Google Scholar 

  165. A. V. Zakhmatov, A. Yu. Borodin, A. A. Povol'skikh, et al., in: Public Health and Education in 21st Century (Proc. 4th Int. Sci.-Pract. Conf.) [in Russian], Russian Univ. of Peoples Friendship, Moscow (2003), pp. 246–247.

    Google Scholar 

  166. G. Casy, Tetrahedron Lett., 33(52), 8159–8162 (1992).

    Google Scholar 

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Koz'minykh, V.O., Koz'minykh, E.N. Synthesis, Structure, and Biological Activity of Acylpyruvic Acids and Related 2-Imino Derivatives (A Review). Pharmaceutical Chemistry Journal 38, 67–77 (2004). https://doi.org/10.1023/B:PHAC.0000032482.69814.90

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