A total of 32 patients (21 with reversible and 11 with chronic Korsakov's syndrome of traumatic origin) and 20 healthy controls were studied. Visual and spectral coherence analysis was applied to EEG recordings and the three-dimensional localization of equivalent dipole sources of β1 activity in the frequency range 13–20 Hz. Stable increases in the coherence of EEG β1 activity generated by a limited number of sources (mostly frontobasal and brainstem locations) had negative prognostic significance in Korsakov's syndrome. Comparison with clinical data allow this EEG phenomenon to be linked to the inhibitory state of the corresponding cortical zones.
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V. M. Banshchikov and I. V. Borzenkov, Korsakov's Syndrome (Clinical Features, Diagnosis, and Course) [in Russian], Moscow (1971).
J. Bendat and A. Piersol, Measurement and Analysis of Random Processes [Russian translation], Mir, Moscow (1974).
G. N. Boldyreva and L. A. Zhavoronkova, “Characteristics of interhemisphere EEG interactions in assessing the functional state of the human brain,” Zh. Vyssh. Nerv. Deyat., 39, No. 2, 215–220 (1989).
G. N. Boldyreva, Electroencephalogram of the Human Brain in Lesions of Diencephalic and Limbic Structures [in Russian], Nauka, Moscow (2000).
I. V. Borzenkov, Korsakov's Syndrome (Clinical Features, Diagnosis, and Questions in the Pathogenesis of Syndrome Formation) [in Russian], Dissertation for Doctorate in Medical Sciences, Perm' (1970).
V. V. Gnezditskii, The EEG Inverse Problem and Clinical Electroencephalography [in Russian], Taganrog (2000).
O. M. Grindel', V. G. Voronov, N. V. Romanova, et al., “Intercentral EEG relationships in regressing and chronic post-traumatic Korsakov's syndrome,” Zh. Vyssh. Nerv. Deyat., 51, No. 5, 572–582 (2001).
A. M. Ivanitskii, A. R. Nikolaev, and G. A. Ivanitskii, Interaction of Cortical Areas in Verbal Thought: Proceedings of the XVIII Congress of the I. P. Pavlov Physiological Society [in Russian], Kazan' (2001), p. 99.
N. K. Kiyashchenko, Memory Impairments in Local Brain Lesions [in Russian], Moscow (1973).
Yu. M. Kopletov and V. V. Gnezditskii, “Analysis of 'scalp potential fields' and three-dimensional localization of the sources of epileptic activity in the human brain,” Zh. Nevropatol. Psikhiat., 89, No. 6, 11–18 (1989).
L. M. Puchinksaya, “EEG of the somatosensory area of the human brain in the state of motor readiness and during wrist movements,” Zh. Vyssh. Nerv. Deyat., 22, No. 2, 368–376 (1972).
M. N. Rusalova and M. B. Kostyunina, “Frequency-amplitude characteristics of the left and right hemispheres during the mental reproduction of emotionally colored images,” Zh. Fiziol. Chel., 25, No. 5, 50–56 (1999).
V. S. Rusinov, O. M. Grindel', N. N. Bragina, et al., “The 'locked in' person and characteristics of the electrical activity of his brain,” Zh. Vyssh. Nerv. Deyat., 40, No. 2, 218–228 (1990).
M. V. Semenova-Tyan-Shanskaya, “Korsakov's syndrome of traumatic origin (development, structure, course),” Zh. Nevropatol. Psikhiat., 76, No. 8, 1191–1195 (1976).
V. B. Strelets, N. N. Danilova, and I. V. Kornilova, “EEG rhythms and psychological measures of emotions in reactive depression,” Zh. Vyssh. Nerv. Deyat., 47, No. 1, 11–20 (1997).
S. Wilks, Mathematical Statistics [in Russian], Nauka, Moscow (1967).
S. V. Urakov, Korsakov's Syndrome in Patients with Craniocerebral Trauma [in Russian], Dissertation for doctorate in Medical Sciences, Moscow (1999).
D. A. Farber and V. I. Kirpichev, “Electroencephalographic correlates of individual features of mental ability in adolescents,” Zh. Vyssh. Nerv. Deyat., 35, 649–656 (1985).
E. V. Sharova, G. N. Boldyreva, N. N. Bragina, and M. A. Kulikov, “Adaptive-compensatory rearrangements of intrahemisphere interactions of electrical processes in the human brain in conditions of stem lesions,” Zh. Vyssh. Nerv. Deyat., 43, No. 6, 1089–1095 (1993).
E. V. Sharova, E. R. Obraztsova, O. S. Zaitsev, et al., “EEG characteristics in post-traumatic Korsakov's syndrome,” Zh. Nevrol. Psikhiat., 101, No. 5, 32–38 (2001).
Y. Gambarelli, G. Gurinel, L. Cherrot, and M. Mattel, “Computerized tomography,” in: Anatomical Atlas of Sections of the Human Body, Anat. Radiol. Scan, Berlin (1977).
F. Lopes da Silva, “Neural mechanisms underlying brain waves: from neural membranes to networks,” EEG Clin. Neurophysiol., 79, 81 (1991).
G. Pfurtchellef, “Central beta-rhythm during sensomotor activities in man,” EEG Clin. Neurophysiol., 51, No. 3, 150–162 (1981).
W. J. Ray and H. W. Cole, “EEG activity during cognitive processing: influence of attentional factors,” Psychophysiology, 3, 43–48 (1985).
B. Schack, S. Mescha, and A. Chen, “The description of synchronization phases during cognitive tasks by instantaneous EEG and MEG coherence,” EEG Clin. Neurophysiol., 103, 157 (1997).
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Obraztsova, E.R., Sharova, E.V., Zaitsev, O.S. et al. Characteristics of Brain Bioelectrical Activity in Post-Traumatic Korsakov's Syndrome. Neurosci Behav Physiol 34, 825–831 (2004). https://doi.org/10.1023/B:NEAB.0000038135.20032.fe
- craniocerebral trauma
- Korsakov's syndrome