Skip to main content
Log in

Cladosporium and respiratory allergy: Diagnostic implications in Saudi Arabia

  • Published:
Mycopathologia Aims and scope Submit manuscript

Abstract

An allergological study to evaluate allergenicity to Cladosporium, Burkard 7-Day Volumetric Spore Trap and Personal Volumetric air sampler (viable mode) were employed to conduct air sampling for 12 months in three regions of Saudi Arabia. The study was extended for a continuous 3rd year at one site. Skin prick testing (SPT) was also conducted on 605 allergic individuals using commercial extracts of C. herbarum. Cladosporium emerged to be the most prevalent genus in the outdoor environment constituting up to 25% of all fungal spores in the dry region and 37.1 and 41.2% in two coastal cities respectively. Amongst the species C. sphaerospermum, C. macrocarpum, C. cladosporioides and C. herbarum were noted. Maximum hourly concentrations up to 14 × 103 m−3 were recorded in coastal region during winter months. Morning concentrations were higher at both city sites compared to afternoon concentration. SPT result revealed an overall 19.67% positive reactions with majority showing mild reactions.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Al-Frayh AR, Hasnain SM, Harfi HA. Respiratory allergy and aeroallergens in Saudi Arabia. J Allergy Clin Immunol 1989; 83(1): 198.

    Google Scholar 

  2. Al-Frayh AR, Gad-El-Rab MO, Al-Najjar AR, Hasnain SM. A comparative study of immediate skin test reactivity to inhalant allergens in asthmatic children of two different regions in Saudi Arabia. Ann Saudi Med 1992; 12(5): 468–471.

    Google Scholar 

  3. Al-Frayh AR. Asthma patterns in Saudi Arabian Children. J Royal Soc Health 1990; 110(3): 98–100.

    CAS  Google Scholar 

  4. A Review. Epidemiological and socio-economic aspects of allergic diseases. Clin Allergy 1986; 16(Suppl): 11–17.

    Google Scholar 

  5. Solomon WR. Aerobiology and inhalant allergens. I. Pollen and fungi. In: Middleton E, Reed CE and Ellis EF, eds. Allergy: Principles and Practice. St. Louis: CV Mosby, 1978: 56–60.

    Google Scholar 

  6. Burge HA. Fungus Allergens. Clin Rev Allergy 1985; 3: 319–329.

    CAS  PubMed  Google Scholar 

  7. Al-Frayh AR, Hasnain SM, Wilson JD, Harfi HA. Fungal Allergens in the Atmosphere of Riyadh: A Preliminary Communication. Ann Saudi Med 1988; 8(4): 248–251.

    Google Scholar 

  8. Hasnain SM, Al-Frayh AR, Thorogood R, et al. Seasonal periodicities of fungal allergens in the atmosphere of Riyadh. Ann Saudi Med 1989; 9(4): 337–343.

    Google Scholar 

  9. Hasnain SM, Wilson JD, Newhook FJ. Fungal allergy and respiratory diseases. NZ Med J 1985; 98: 342–346.

    CAS  Google Scholar 

  10. Frankland AW, Davies RR. Allergie Auxspores De Moisissures en Angleterre. Le Poumin et le Coueur 1965; 21: 11–23.

    CAS  Google Scholar 

  11. Aukrust L. Allergens in Cladosporium herbarum. In: Oehling A eds. Advances in Allergology, New York: Perganon Press, 1980.

    Google Scholar 

  12. Salvaggio J, Aukrust L. Mold-induced asthma. J Allergy Clin Immunol 1981;68: 327–346.

    Article  CAS  PubMed  Google Scholar 

  13. Ellis MB. Dematiaceous hyphomycete Commonwealth Mycological Institute, Surrrey England, 1971: 289–292.

  14. Ellis MB. More dematiacious hypomycete. Commonwealth Mycological Institute, Surrey, England, 1976: 325–344.

    Google Scholar 

  15. Marsh, DG, Goodfriend L, King TP, et al. Allergen nomenclature. Clin Allergy 1988; 18: 201–209.

    Google Scholar 

  16. Aukrust L, Borch SM. Partial purification and characterization of two Cladosporium herbarum allergens. Int Arch Allergy Appl. Immunol 1979; 60: 68–79.

    CAS  PubMed  Google Scholar 

  17. Collins-Williams C. Nizami RM, Lamenza C, Chui AW. Nasal provocative testing with molds in the diagnosis of perennial allergic rhinitis. Ann Allergy 1972; 30: 557.

    CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Syed M. Hasnain.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Hasnain, S.M., Al-Frayh, A.S., Al-Suwaine, A. et al. Cladosporium and respiratory allergy: Diagnostic implications in Saudi Arabia. Mycopathologia 157, 171–179 (2004). https://doi.org/10.1023/B:MYCO.0000020592.72238.a6

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1023/B:MYCO.0000020592.72238.a6

Navigation