Skip to main content
Log in

Preparation, purification and quality control of 131I-m-iodobenzylguanidine (MIBG)*

  • Published:
Journal of Radioanalytical and Nuclear Chemistry Aims and scope Submit manuscript

Abstract

Iodination of meta-iodobenzylguanidine was carried out at optimum conditions. The labeling yield at these conditions was more than 95%. Further purification of the prepared compound increased the radiochemical purity to more than of 99.5%, this high purity was revealed in the quality of the images resulting from the use of the prepared compounds.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. D. M. Wieland, J. Wu, L. E. Brown, T. J. Manger, D. P. Swanson, W. H. Bierwalters, J. Nucl. Med., 21 (1980) 349.

    Google Scholar 

  2. C. A. Hoefnagel, Thesis, University of Amsterdam, 1989.

  3. W. H. Bierwalters, Nucl. Med. Biol., 14 (1987) 183.

    Google Scholar 

  4. A. J. Mc Ewan, P. Wyeth, D. Ackery, Appl. Radiation Isotopes, 37 (1986) 765.

    Google Scholar 

  5. G. Prabhakav, K. S. Mehra, N. Ramamoorthy, S. Chahopadhyay, R. Oommen, S. Narasimhan, N. A. Nair, S. Gunasekaran, Appl. Radiation Isotopes, 50 (1999) 1011.

    Google Scholar 

  6. O. Geatti, B. Shapiro, J. C. Sisson, R. J. Hutchinson, S. Mallehe, D. Eyer, W. H. Beierwates, J. Nucl. Med., 26 (1985) 736.

    Google Scholar 

  7. A. R. Wafelmun, M. C. P. Konings, C. A. Hoefnagel, R. A. A. Maes, J. H. Beijnen, Appl. Radiation Isotopes, 10 (1994) 997.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Yassine, T., Bakir, M.A., Shanan, S. et al. Preparation, purification and quality control of 131I-m-iodobenzylguanidine (MIBG)*. Journal of Radioanalytical and Nuclear Chemistry 258, 635–637 (2003). https://doi.org/10.1023/B:JRNC.0000011761.84999.f7

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1023/B:JRNC.0000011761.84999.f7

Keywords

Navigation