Abstract
Iodination of meta-iodobenzylguanidine was carried out at optimum conditions. The labeling yield at these conditions was more than 95%. Further purification of the prepared compound increased the radiochemical purity to more than of 99.5%, this high purity was revealed in the quality of the images resulting from the use of the prepared compounds.
Similar content being viewed by others
References
D. M. Wieland, J. Wu, L. E. Brown, T. J. Manger, D. P. Swanson, W. H. Bierwalters, J. Nucl. Med., 21 (1980) 349.
C. A. Hoefnagel, Thesis, University of Amsterdam, 1989.
W. H. Bierwalters, Nucl. Med. Biol., 14 (1987) 183.
A. J. Mc Ewan, P. Wyeth, D. Ackery, Appl. Radiation Isotopes, 37 (1986) 765.
G. Prabhakav, K. S. Mehra, N. Ramamoorthy, S. Chahopadhyay, R. Oommen, S. Narasimhan, N. A. Nair, S. Gunasekaran, Appl. Radiation Isotopes, 50 (1999) 1011.
O. Geatti, B. Shapiro, J. C. Sisson, R. J. Hutchinson, S. Mallehe, D. Eyer, W. H. Beierwates, J. Nucl. Med., 26 (1985) 736.
A. R. Wafelmun, M. C. P. Konings, C. A. Hoefnagel, R. A. A. Maes, J. H. Beijnen, Appl. Radiation Isotopes, 10 (1994) 997.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Yassine, T., Bakir, M.A., Shanan, S. et al. Preparation, purification and quality control of 131I-m-iodobenzylguanidine (MIBG)*. Journal of Radioanalytical and Nuclear Chemistry 258, 635–637 (2003). https://doi.org/10.1023/B:JRNC.0000011761.84999.f7
Issue Date:
DOI: https://doi.org/10.1023/B:JRNC.0000011761.84999.f7