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Synthesizing Macrocycles under Thermodynamic Control – Dynamic Combinatorial Libraries and Templates

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Abstract

An effective way to synthesize macrocycles using a dynamic combinatorial library is demonstrated for the reaction of pyridine-2,6-dicarbaldehydes with several long diamines. According to the template ions present, a given library can be shifted towards several macrocycles as desired.

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References

  1. U. Lüning: Reaktivität, Reaktionswege, Mechanismen. Ein Begleitbuch zur Organischen Chemie im Grundstudium, Spektrum Hochschultaschenbuch, Spektrum Akademischer Verlag (1997).

  2. U. Lüning, F. Fahrenkrug, and M. Hagen: Eur. J. Org. Chem. 2161-2163 (2001).

  3. U. Lüning, M. Abbass, and F. Fahrenkrug: Eur. J. Org. Chem. 3294-3303 (2002).

  4. S.L. Roberts, R.L.E. Furlan, S. Otto, and J.K.M. Sanders: Org. Biomol. Chem.1, 1625-1633 (2003) and refs. cited.

  5. J.-M. Lehn: Chem. Eur. J. 5, 2455-2463 (1999).

    Google Scholar 

  6. S.J. Rowan, S.J. Cantrill, G.R.L. Cousins, J.K.M. Sanders, and J. F. Stoddart: Angew. Chem. 114, 938-993 (2002); Int. Ed. 41, 898-952 (2002).

    Google Scholar 

  7. U. Lüning, Liebigs Ann. Chem. 949-955 (1987).

  8. U. Lüning, R. Baumstark, K. Peters, and H.G. von Schnering: Liebigs Ann. Chem. 129-143 (1990).

  9. U. Lüning, R. Baumstark, and M. Müller: Liebigs Ann. Chem. 987-998 (1991).

  10. U. Lüning and M. Müller: Liebigs Ann. Chem. 367-374 (1989).

  11. M.J. Marsella, H.D. Maynard, and R.H. Grubbs: Angew. Chem. 109, 1147-1150 (1997); Int. Ed. 36, 1101-1103 (1997).

    Google Scholar 

  12. G.R.L. Cousins, R.L.E. Furlan, Y.-F. Ng, J.E. Redman, and J.K.M. Sanders: Angew. Chem. 113, 437-442 (2001); Int. Ed. 40, 423-428 (2001); and references cited therein.

    Google Scholar 

  13. O. Storm and U. Lüning: Chem. Eur. J. 8, 793-798 (2002).

    Google Scholar 

  14. S. Otto, R.L.E. Furlan, and J.K.M. Sanders: Science 297, 590-593 (2002).

    Google Scholar 

  15. B. Brisig, J.K.M. Sanders, and S. Otto: Angew. Chem. 115, 1308-1311 (2003); Int. Ed. 42, 1270-1273 (2003).

    Google Scholar 

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Lüning, U. Synthesizing Macrocycles under Thermodynamic Control – Dynamic Combinatorial Libraries and Templates. Journal of Inclusion Phenomena 49, 81–84 (2004). https://doi.org/10.1023/B:JIPH.0000031117.97865.b1

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  • DOI: https://doi.org/10.1023/B:JIPH.0000031117.97865.b1

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