Abstract
An effective way to synthesize macrocycles using a dynamic combinatorial library is demonstrated for the reaction of pyridine-2,6-dicarbaldehydes with several long diamines. According to the template ions present, a given library can be shifted towards several macrocycles as desired.
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Lüning, U. Synthesizing Macrocycles under Thermodynamic Control – Dynamic Combinatorial Libraries and Templates. Journal of Inclusion Phenomena 49, 81–84 (2004). https://doi.org/10.1023/B:JIPH.0000031117.97865.b1
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DOI: https://doi.org/10.1023/B:JIPH.0000031117.97865.b1