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Birth Weight Discordance in Spontaneous Versus Induced Twins: Impact on Perinatal Outcome

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Abstract

Purpose: To compare the rate of birth weight discordance and perinatal outcome of twin pregnancies after assisted reproduction with that of spontaneous twins.

Method: A total of 12,920 deliveries were analyzed retrospectively. Seventy-five twin pregnancies after ART were compared to the 94 spontaneous counterparts. Birth weight discordance was defined as a difference of 20% or more.

Results: Discordance rate was elevated (25.3% vs. 17.0%) among ART twins. SGA was increased and NICU admission was more frequent in discordant group. Unlike-sexed twins were more prevalent (73.7% vs. 37.5%) among discordants after ART.

Conclusions: ART can increase discordance rate which can elevate perinatal risk.

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References

  1. Cooperstock MS, Tummaru R, Bakewell J, Schramm W: Twin birth weight discordance and risk of preterm birth. Am J Obstet Gynecol 2000;183(1):63-67

    Google Scholar 

  2. Redman ME, Blackwell SC, Refuerzo JS, Kruger M, Naccasha N, Hassan SS, Berry SM: The ninety-fifth percentile for growth discordance predicts complications of twin pregnancy. Am J Obstet Gynecol 2002;87(3):667-671

    Google Scholar 

  3. Demissie K, Ananth CV, Martin J, Hanley ML, MacDorman MF, Rhoads GG: Fetal and neonatal mortality among twin gestations in the United States: The role of intrapair birth weight discordance. Obstet Gynecol 2002;100(3):474-480

    Google Scholar 

  4. Audibert F, Boullier M, Kerbrat V, Vial M, Boithias C, Frydman R: Growth discordance in dichorionic twin pregnancies: Risk factors, diagnosis and management. J Gynecol Obstet Biol Reprod 2002;31(Suppl 1):2S15-2S24

    Google Scholar 

  5. Victoria A, Mora G, Arias F: Perinatal outcome, placental pathology, and severity of discordance in monochorionic and dichorionic twins. Obstet Gynecol 2001;97(2):310-315

    Google Scholar 

  6. Lambalk CB, van Hoof M: Natural versus induced twinning and pregnancy outcome: a Dutch nationwide survey of primiparous dizygotic twin deliveries. Fertil Steril 2001;75(4):731-736

    Google Scholar 

  7. Koudstaal J, Bruinse HW, Helmerhorst FM, Vermeiden JP, Willemsen WN, Visser GH: Obstetric outcome of twin pregnancies after in-vitro fertilization: A matched control study in four Dutch university hospitals. Hum Reprod 2000;15(4):935-940

    Google Scholar 

  8. Daniel Y, Ochshorn Y, Fait G, Geva E, Bar-Am A, Lessing JB: Analysis of 104 twin pregnancies conceived with assisted reproductive technologies and 193 spontaneously conceived twin pregnancies. Fertil Steril 2000;74(4):683-689

    Google Scholar 

  9. Zádori J, Kozinszky Z, Orvos H, Katona M, Pál A, Kovács L: Dilemma of increased obstetric risk in pregnancies following IVF-ET. J Assist Reprod Genet 2003;20(6):216-221

    Google Scholar 

  10. Hardy K, Wright C, Rice S, Tachataki M, Roberts R, Morgan D, Spanos S, Taylor D: Future developments in assisted reproduction in humans. Reproduction 2002;123(2):171-183

    Google Scholar 

  11. Westwood M, Gibson JM, Sooranna SR, Ward S, Neilson JP, Bajoria R: Genes and placenta as modulator of fetal growth: Evidence from insulin-like growth factor axis in twins with discordant growth. Mol Hum Reprod 2001;7(4):387-395

    Google Scholar 

  12. Kalish RB, Chasen ST, Gupta M, Sharma G, Perni SC, Chervenak FA: First trimester prediction of growth discordance in twin gestations. Am J Obstet Gynecol 2003;189(3):706-709

    Google Scholar 

  13. Blumrosen E, Goldman RD, Blickstein I: Growth discordance and the effect of a male twin on birth weight of its female co-twin: A population based study. J Perinat Med 2002;30(6):510-513

    Google Scholar 

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Correspondence to J. Zádori.

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Zádori, J., Kozinszky, Z., Orvos, H. et al. Birth Weight Discordance in Spontaneous Versus Induced Twins: Impact on Perinatal Outcome. J Assist Reprod Genet 21, 85–88 (2004). https://doi.org/10.1023/B:JARG.0000027019.87795.4e

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  • DOI: https://doi.org/10.1023/B:JARG.0000027019.87795.4e

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