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Studying Interactions, Reactions, and Perceptions: Can Genetic Disorders Serve as Behavioral Proxies?

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Abstract

Different genetic disorders predispose individuals to display specific, etiology-related profiles, personalities, and maladaptive behaviors. Using groups with genetic etiologies as stand-ins or proxies for a specific behavior or set of behaviors, one can then examine how others in the child's environment react and whether such reactions are limited to a particular disorder or occur generally to all individuals showing that behavior. Just as twins, adopted, and institutionalized children have all been used as natural experiments to tell us about typical development, so too can groups with specific genetic syndromes help us to understand the nature and mechanisms of the reactions and behaviors of others.

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Reference

  • Allanson, J. E., O'Hara, P., Farkas, G., & Nair, R. C. (1993). Anthropometric craniofacial pattern profiles in Down syndrome. American Journal of Medical Genetics, 47, 748-752.

    Google Scholar 

  • Bell, R. Q. (1979). Parent, child, and reciprocal influences. American Psychologist, 34, 821-826.

    Google Scholar 

  • Bellugi, U., Mills, D., Jernigan, T., Hickok, G., & Galaburda, A. (1999). Linking cognition, brain structure, and brain function in Williams syndrome. In H. Tager-Flusberg (Ed.), Neurodevelopmental disorders (pp. 111-136). Cambridge: MIT Press.

    Google Scholar 

  • Cahill, B. M., & Glidden, L. M. (1996). Influence of child diagnosis on family and parent functioning: Down syndrome versus other disabilities. American Journal on Mental Retardation, 101, 149-160.

    Google Scholar 

  • Cassidy, S. B. (1984). Prader-Willi syndrome. Current Problems in Pediatrics, 14, 1-55.

    Google Scholar 

  • Chapman, R. S., & Hesketh, L. J. (2000). Behavioral phenotype of individuals with Down syndrome. Mental Retardation and Developmental Disabilities Research Reviews, 6, 84-95.

    Google Scholar 

  • Dimitropoulos, A., Feurer, I. D., Butler, M. G., & Thompson, T. (2001). Emergence of compulsive behavior and tantrums in children with Prader-Willi syndrome. American Journal on Mental Retardation, 106, 39-51.

    Google Scholar 

  • Dykens, E. M. (1995). Measuring behavioral phenotypes: Provocations from the “New Genetics.” American Journal on Mental Retardation, 99, 522-532.

    Google Scholar 

  • Dykens, E. M. (2002). Are jigsaw puzzle skills spared in persons with Prader-Willi syndrome? Journal of Child Psychology and Psychiatry, 43, 343-352.

    Google Scholar 

  • Dykens, E. M. (in press). Maladaptive behaviors and compulsions in Prader-Willi syndrome: New insights from older adults. American Journal on Mental Retardation.

  • Dykens, E. M. (2003). Anxiety, fears, and phobias in persons with Williams syndrome. Developmental Neuropsychology, 23, 293-318.

    Google Scholar 

  • Dykens, E. M., Leckman, J. F., & Cassidy, S. B. (1996). Obsessions and compulsions in Prader-Willi syndrome. Journal of Child Psychology and Psychiatry, 37, 995-1002.

    Google Scholar 

  • Dykens, E. M., & Rosner, B. A. (1999). Refining behavioral phenotypes: Personality-motivation in Williams and Prader-Willi syndromes. American Journal on Mental Retardation, 104, 158-169.

    Google Scholar 

  • Dykens, E. M., Shah, B., Sagun, J., Beck, T., & King, B. Y. (2002). Maladaptive behavior in children and adolescents with Down syndrome: Community and clinic samples. Journal of Intellectual Disability Research, 46, 484-492.

    Google Scholar 

  • Fidler, D. J. (2003). Parental vocalizations and perceived immaturity in Down syndrome. American Journal on Mental Retardation, 108, 425-434.

    Google Scholar 

  • Fidler, D. J., & Hodapp, R. M. (1999). Craniofacial maturity and perceived personality in children with Down syndrome. American Journal on Mental Retardation, 104, 410-421.

    Google Scholar 

  • Fidler, D. J., Hodapp, R. M., & Dykens, E. M. (2002). Behavioral phenotypes and special education: Parent report of educational issues for children with Down syndrome, Prader-Willi syndrome, and Williams syndrome. Journal of Special Education, 36, 80-88.

    Google Scholar 

  • Graham, S. (1994). Classroom motivation from an attributional perspective. In H. F. O'Neil, & M. Drillings (Eds.), Motivation: Theory and research (pp. 31-48). Hillsdale, NJ: Lawrence Erlbaum.

    Google Scholar 

  • Hanson, M., & Hanline, M. F. (1990). Parenting a child with a disability: A longitudinal study of parental stress and adaptation. Journal of Early Intervention, 14, 234-248.

    Google Scholar 

  • Hodapp, R. M. (1997). Direct and indirect behavioral effects of different genetic mental retardation disorders. American Journal on Mental Retardation, 102, 67-79.

    Google Scholar 

  • Hodapp, R. M., Evans, D. W., & Gray, F. L. (1999). Intellectual development in children with Down syndrome. In J. Rondal, J. Perera, & L. Nadel (Eds.), Down syndrome: A review of current knowledge (pp. 124-132). London: Whurr.

    Google Scholar 

  • Hodapp, R. M., Ly, T. M., Fidler, D. J., & Ricci, L. A. (2001). Less stress, more rewarding: Parenting children with Down syndrome. Parenting: Science and Practice, 1, 317-337.

    Google Scholar 

  • Hodapp, R. M., & Ricci, L. A. (2002). Behavioral phenotypes and educational practice: The unrealized connection. In G. O'Brien & O. Udwin (Eds.), Behavioral phenotypes in clinical practice (pp. 137-151). London: MacKeith Press.

    Google Scholar 

  • Hodapp, R. M., Ricci, L. A., Ly, T. M., & Fidler, D. J. (2003). The effects of the child with Down syndrome on maternal stress. British Journal of Developmental Psychology, 22, 137-151.

    Google Scholar 

  • Hornby, G. (1995). Fathers' views of the effects on their families of children with Down syndrome. Journal of Child and Family Studies, 4, 103-117.

    Google Scholar 

  • Jarrold, C., Baddeley, A. D., Hewes, A. K., & Phillips, C. (2001). A longitudinal assessment of diverging verbal and non-verbal abilities in the Williams syndrome phenotype. Cortex, 37, 423-431.

    Google Scholar 

  • Kasari, C., Mundy, P., Yirmiya, N., & Sigman, M. (1990). Affect and attention in children with Down syndrome. American Journal on Mental Retardation, 95, 55-67.

    Google Scholar 

  • Ly, T. M., & Hodapp, R. M. (2002). Maternal attributions of child noncompliance in children with mental retardation: Down syndrome versus other etiologies. Journal of Developmental and Behavioral Pediatrics, 23, 322-329.

    Google Scholar 

  • Ly, T. M., & Hodapp, R. M. (2003). Children with Prader-Willi syndrome vs. Williams syndrome: Parents'attributional cues during a jigsaw puzzle task (unpublished).

  • Mervis, C. B., Morris, C. A., Bertrand, J. M., & Robinson, B. F. (1999). Williams syndrome: Findings from an integrated program of research. In H. Tager-Flusberg (Ed.), Neurodevelopmental disorders (pp. 65-110). Cambridge: MIT Press.

    Google Scholar 

  • Miller, J. (1999). Profiles of language development in children with Down syndrome. In J. F. Miller, M. Leddy, & L. A. Leavitt (Eds.), Improving the communication of people with Down syndrome (pp. 11-39). Baltimore, MD: Paul H. Brookes.

    Google Scholar 

  • Noh, S., Dumas, J. E., Wolf, L. C., & Fisman, S. N. (1989). Delineating sources of stress in parents of exceptional children. Family Relations, 38, 456-461.

    Google Scholar 

  • Pueschel, S. R., Gallagher, P. L., Zartler, A. S., & Pezzullo, J. C. (1986). Cognitive and learning profiles in children with Down syndrome. Research in Developmental Disabilities, 8, 21-37.

    Google Scholar 

  • Roach, M. A., Orsmond, G. I., & Barratt, M. S. (1999). Mothers and fathers of children with Down syndrome: Parental stress and involvement in childcare. American Journal on Mental Retardation, 104, 422-436.

    Google Scholar 

  • Rutter, M., Pickles, A., Murray, R., & Eaves, L. (2001). Testing hypotheses on specific environmental causal effects on behavior. Psychological Bulletin, 127, 291-324.

    Google Scholar 

  • Rutter, M., Thorpe, K., Greenwood, R., Northstone, K., & Golding, J. (2003). Twins as a natural experiment to study the causes of mild language delay: I: Design, twin-singleton differences in language, and obstetric risks. Journal of Child Psychology and Psychiatry, 44, 326-341.

    Google Scholar 

  • Thorpe, K., Rutter, M., & Greenwood, R. (2003). Twins as a natural experiment to study the causes of mild language delay: II: Family interaction risk factors. Journal of Child Psychology and Psychiatry, 44, 342-355.

    Google Scholar 

  • Wishart, J. G., & Johnston, F. H. (1990). The effects of experience on attribution of a stereotyped personality to children with Down's syndrome. Journal of Mental Deficiency Research, 34, 409-420.

    Google Scholar 

  • Zebrowitz, L. A. (1997). Reading faces: Window to the soul? Boulder, CO: Westview Press.

    Google Scholar 

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Correspondence to Robert M. Hodapp.

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Hodapp, R.M. Studying Interactions, Reactions, and Perceptions: Can Genetic Disorders Serve as Behavioral Proxies?. J Autism Dev Disord 34, 29–34 (2004). https://doi.org/10.1023/B:JADD.0000018071.02942.00

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  • DOI: https://doi.org/10.1023/B:JADD.0000018071.02942.00

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