Abstract
Background: Most patients who develop metastatic carcinoma to the choroid are managed by local radiation or chemotherapy. Since transpupillary thermotherapy (TTT) is currently gaining attention as an optional treatment for choroidal melanomas and hemangiomas, we sought to determine whether TTT is suitable for treatment of solitary choroidal metastasis at the posterior pole. Method: We report on a patient with decreased vision due to a serous macular detachment in a eye with a solitary choroidal metastasis from breast carcinoma, who was managed by TTT. Results: After two months of follow up, total re-absorption of the serous macular detachment was achieved and the patient recovered full visual acuity in the treated eye. The choroidal mass became atrophic and hyperpigmentation of the retinal pigment epithelium and retinal folds in the macular region were observed. After six months of TTT, the ocular picture remained unchanged. Conclusion: TTT can be considered an acceptable therapeutic option for solitary choroidal metastasis associated with serous retinal detachment.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Augsburger JJ, Guthoff R. Metastatic cancer to the eye. In: Yanoff M, Duker JS (eds) Ophthalmology. London: Mosby International Ltd., 1999; 9: 4.1–4.6.
Shields CL, Shields JA, Gross NE, Schwartz GP, Lally SE. Survey of 520 eyes with uveal metastasis. Ophthalmology 1997; 104: 1265–1276.
Shields JA, Shields CL. Intraocular tumors: a text and atlas. Philadelphia: WB Saunders, 1992; 8: 117–136.
Oosterhuis JA, Journee-de Korver JG, Kakebeeke-Kemme HM, Blecker JC. Transpupillary thermotherapy in choroidal melanomas. Arch Ophthalmol 1995; 113: 315–321.
Garcia-Arumi J, Ramsay LS, Guraya BC. Transpupillary thermotherapy for circumscribed choroidal hemangiomas. Ophthalmology 2000; 107: 351–356.
Kiratli H, Bilgiç S. Solitary choroidal metastasis managed by transpupillary thermotherapy. Eye 2000; 14: 799–800.
Puri P, Gupta M, Rundle PA, Rennie IG. Indocyanine green augmented transpupillary thermotherapy in the management of choroidal metastasis from breast carcinoma. Eye 2001; 15: 515–518.
Journee-de Korver JG, Oosterhuis JA, de Wolff-Rovendal D, Kakebeeke-Keeme HM. Histopathological findings in human choroidal melanomas after transpupillary thermotherapy. Br J Ophthalmol 1997; 81: 234–239.
Oosterhuis JA, Journee-de Korver JG, Keunen. Transpupillary thermotherapy. Results in 50 patients with choroidal melanoma. Arch Ophthalmol 1998; 116: 157–162.
Svaasand LO, Boerslid T, Oeveraasen M. Thermal and optical properties of living tissue:application to laser-induced hyperthermia. Lasers Surg Med 1985; 5: 589–602.
Journee-de Korver JG, Keunen JEE. Thermotherapy in the management of choroidal melanoma. Prog Ret Eye Res 2002; 21(3): 303–317.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Vianna, R.N.G., Pena, R., Muralha, A. et al. Transpupillary Thermotherapy in the Treatment of Choroidal Metastasis from Breast Carcinoma. Int Ophthalmol 25, 23–26 (2004). https://doi.org/10.1023/B:INTE.0000018525.92811.e4
Issue Date:
DOI: https://doi.org/10.1023/B:INTE.0000018525.92811.e4