Abstract
Purpose: To evaluate the aqueous levels of transforming growth factor beta-2 (TGF-β2) in open angle glaucoma patients. Methods: The aqueous levels of active TGF-β2 were detected in 17 eyes of 17 patients using ELISA method. The control group consisted of 6 cataract extracted patients. Results: Mean age of the patients (60.8 ± 8.8 years) was similar to that of the controls (57.5 ± 9.8 years) (p = 0.516). Levels of TGF-β2 in aqueous samples of glaucoma patients (2.74 ± 1.23 ng/ml) were found to be elevated when compared to those of controls (1.67 ± 0.32 ng/ml) (p = 0.020). Conclusion: We might suggest that the elevated levels of TGF-β2 in the aqueous of glaucoma patients could play a role in the pathogenesis of glaucoma.
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Ozcan, A.A., Ozdemir, N. & Canataroglu, A. The Aqueous Levels of TGF-β2 in Patients with Glaucoma. Int Ophthalmol 25, 19–22 (2004). https://doi.org/10.1023/B:INTE.0000018524.48581.79
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DOI: https://doi.org/10.1023/B:INTE.0000018524.48581.79