Abstract
The effects of biphenol and quinone derivatives on the radiation-initiated dephosphorylation of 1-glycerophosphate under various conditions were studied. It was found that in deaerated media, para-and ortho-quinone derivatives inhibited the formation of the phosphate ion by a factor of 1.8–1.9, and hydroquinone and pyrocatechol derivatives inhibited this reaction by a factor of 1.3–1.4, whereas 5-methylresorcinol and 2-methoxyphenol had no effect on the elimination of inorganic phosphate. It was demonstrated that a decrease in the radiation-chemical yields of the phosphate anion was due to the oxidation of 1-glycerophosphate radicals, which were formed under γ-radiolysis in aqueous solutions, by quinones.
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REFERENCES
von Sonntag, C., The Chemical Bases of Radiation Biology, London: Taylor and Francis, 1987, p. 504.
Halliwell, B. and Gutteridge, J.M.C., Free Radicals in Biology and Medicine, Oxford: Clarendon, 1999, 3rd ed.
Kisel', M.A., Shadyro, O.I., and Yurkova, I.L., Khim. Vys. Energ., 1997, vol. 31, no. 2, p. 99 [High Energy Chem. (Engl. transl.), 1997, vol. 31, no. 2, p. 80].
Edimecheva, I.P., Kisel, M.A., Shadyro, O.I., Vlasov, A.P., and Yurkova, I.L., Int. J. Radiat.Biol, 1997, vol. 71, no. 5, p. 555.
Kisel, M.A., Shadyro, O.I., and Yurkova, I.L., Int. J. Radiat. Biol., 2002, vol. 78, no. 3, p. 211.
Kisel, M.A., Shadyro, O.I., and Yurkova, I.L., Curr. Top. Biophys., 2000, vol. 24, no. 1, p. 41.
Shadyro, O.I., Yurkova, I.L., and Kisel', M.A., Khim. Vys. Energ., 2000, vol. 34, no. 2, p. 120 [High Energy Chem. (Engl. transl.), 2000, vol. 34, no. 2, p. 89].
Samuni, A. and Neta, P., J. Phys. Chem., 1973, vol. 77, no. 20, p. 2425.
Schuchmann, M.N., Scholes, M.L., Zegota, H., and von Sonntag, C., Int. J. Radiat. Biol., 1995, vol. 68, no. 2, p. 121.
Petryaev, E.P. and Shadyro, O.I., Radiatsionnaya khimiya bifunktsional'nykh organicheskikh soedinenii (Radiation Chemistry of Bifunctional Organic Compounds), Minsk: Izd. Universitetskoe, 1986.
Gohn, M. and Getoff, N., J. Chem. Soc., Faraday Trans., 1977, vol. 73, no. 1, p. 1207.
Gin, F.J. and Morales, F., Anal. Biochem., 1977, vol. 77, no. 1, p. 10.
Davies, M.J., Forni, L.G., and Willson, R.L., Biochem. J., 1988, vol. 255, p. 513.
Richter, H.W., J. Phys. Chem., 1979, vol. 83, p. 1123.
Simic, M. and Hayon, E., Biochem. Biophys. Res. Commun., 1973, vol. 50, no. 2, p. 364.
Franchi, P., Lucarini, M., Pedulli, G., Valgimigli, L., and Lunelli, B., J. Am. Chem. Soc., 1999, vol. 121, no. 3, p. 507.
Ruegge, O. and Fisher, H., Int. J. Chem. Kinet. 1989, vol. 21, p. 703.
Steenken, S., J. Phys. Chem., 1979, vol. 83, no. 5, p. 595.
The Theory of the Photographic Process, James, T.H., Ed., New York: Macmillan, 1977. Translated under the title Teoriya fotograficheskogo protsessa, Leningrad: Khimiya, 1990.
Nonhebel, D. and Walton, J., Free-Radical Chemistry: Structure and Mechanism, Cambridge: Cambridge Univ. Press, 1974. Translated under the title Khimiya svobodnykh raikalov, Moscow: Mir, 1977.
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Pototskaya, T.A., Shadyro, O.I. & Yurkova, I.L. Effects of Biphenol and Quinone Derivatives on the Radiation-Initiated Dephosphorylation of 1-Glycerophosphate. High Energy Chemistry 38, 2–7 (2004). https://doi.org/10.1023/B:HIEC.0000012056.30948.ae
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DOI: https://doi.org/10.1023/B:HIEC.0000012056.30948.ae