Abstract
The (CT) n·(GA) n rich sequences in the upstream and 5′ intron enhancer regions of the sn-glycerol-3-phosphate dehydrogenase (Gpdh) gene in Drosophila melanogaster, its sibling and distantly related species are conserved in their position and in the number of repeats. Using in vitro DNA-footprint analyses we show that the GAGA factor binds to these multiple closely spaced and overlapping conserved (CT) n·(GA) n repeats in D. melanogaster and D. erecta.
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Tchoubrieva, E., Gibson, J. Conserved (CT) n·(GA) n Repeats in the Non-coding Regions at the Gpdh Locus are Binding Sites for the GAGA Factor in Drosophila melanogaster and its Sibling Species. Genetica 121, 55–63 (2004). https://doi.org/10.1023/B:GENE.0000019922.36436.3c
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DOI: https://doi.org/10.1023/B:GENE.0000019922.36436.3c