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Differential effect of insulin-like growth factor I on in vitro gonadotropin subunits expression in Atlantic salmon

Fish Physiology and Biochemistry volume 28, pages 105–106 (2003)Cite this article

Abstract

In the present study a serum-free primary culture of pituitary cells was used to study the direct effect of insulin-like growth factors (IGFs) on gonadotropin gene expression in immature Atlantic salmon. Treatment with IGF I increased the expression of the luteinizing hormone (LH) β subunit in a dose-dependent manner. IGF I and IGF II had similar potencies, but insulin was less effective in stimulating LH-β subunit expression. On the other hand, IGFs or insulin had no effect on the expression of the follicle-stimulating hormone (FSH) β-subunit. The results indicate that the stimulatory effect of IGF I on LH synthesis is exerted through a specific increase of the transcription level of the LH β subunit.

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References

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Authors and Affiliations

  1. Dept. Aquaculture, Swedish, University of Agricultural Sciences, Umeå, Sweden

    M. Schmitz

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  1. M. Schmitz
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Schmitz, M. Differential effect of insulin-like growth factor I on in vitro gonadotropin subunits expression in Atlantic salmon. Fish Physiology and Biochemistry 28, 105–106 (2003). https://doi.org/10.1023/B:FISH.0000030491.40805.96

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  • DOI: https://doi.org/10.1023/B:FISH.0000030491.40805.96

Keywords

  • Direct Effect
  • Luteinizing Hormone
  • Primary Culture
  • Differential Effect
  • Atlantic Salmon

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