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Epidemiological survey of histoplasmine and paracoccidioidine skin reactivity in an agricultural area in Bolívar state, Venezuela

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Abstract

Paracoccidiodomycosis and histoplasmosis are endemic diseases in the south of Venezuela, representing a public health problem. Prevalence of Paracoccidiodes brasiliensis and Histoplasma capsulatum infections were estimated in Monte Ralo, a rural community area of Bolívar state using paracoccidiodine and histoplasmine skin tests. Paracoccidiodine was intradermically injected to 173 persons and readings were made at 24 and 48 h afterwards to 167 persons (97.85%). Reaction was positive in 8.5% (n = 14) at 24 h post-injection and 13.2% (n = 20) at 48 h. Farmers showed the higher percentage of positivity at 24 and 48 h. One hundred-seventy five persons were intradermically injected with histoplasmine but 167 and 157 of them attended for reading of the dermal reaction at 24 and 48 h post-injection respectively. Tests were positive in 25.7% (n = 43) at 24 h and 42.7% (n = 67) at 48 h. Further studies are needed in surrounding places to delimit the endemic area of these mycosis in the Bolívar state. However, epidemiological vigilance of PCM and H should be considered by local health authorities.

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Authors and Affiliations

  1. Departamento de Parasitología y Microbiología, Núcleo Bolívar, Ciudad Bolívar, Venezuela

    Julman Rosiris Cermeño, Isabel Hernández, Gerardo Godoy, Yida Orellán, Ytalia Blanco, Yesenia Guzmán & Frannelly Alcalá

  2. Departamento de Medicina, Escuela de Medicina ‘Dr. Francisco Battistini Casalta’, Complejo Hospitalario Universitario ‘Ruiz y Páez’, Universidad de Oriente, Núcleo Bolívar, Ciudad Bolívar, Venezuela

    Julmery Jesús Cermeño & Ismery Cabello

  3. Instituto de Salud Pública del Estado Bolívar, Distrito Sanitario No 2, Venezuela

    July Josefina Cermeño

  4. Complejo Hospitalario Universitario ‘Ruiz y Páez’, Estado Bolívar, Venezuela

    Teófilo García

  5. Departamento de Ciencias Fisiológicas, Escuela de Medicina ‘Dr. Francisco Batisttini Casalta’, Universidad de Oriente, Núcleo Bolívar, Ciudad Bolívar, Venezuela

    Salvador Penna

Authors
  1. Julman Rosiris Cermeño
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  2. Isabel Hernández
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  3. Julmery Jesús Cermeño
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  5. July Josefina Cermeño
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  8. Ismery Cabello
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  11. Teófilo García
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  12. Salvador Penna
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Correspondence to Julman Rosiris Cermeño.

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Cermeño, J.R., Hernández, I., Cermeño, J.J. et al. Epidemiological survey of histoplasmine and paracoccidioidine skin reactivity in an agricultural area in Bolívar state, Venezuela. Eur J Epidemiol 19, 189–193 (2004). https://doi.org/10.1023/B:EJEP.0000017716.95609.bc

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  • DOI: https://doi.org/10.1023/B:EJEP.0000017716.95609.bc

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