Skip to main content
SpringerLink
Log in

Surface-Ionization Mass Spectrometry of Opium Alkaloids

  • Published:
Chemistry of Natural Compounds Aims and scope

Abstract

Surface ionization of the opium alkaloids morphine, codeine, thebaine, papaverine, and narcotine was investigated by mass spectrometry. It was shown that the alkaloid molecules were ionized with high efficiency through surface ionization. The mass spectra of morphine, codeine, and thebaine exhibited series of lines for quasimolecular ions with elimination of up to nine H atoms from the opiates that was accompanied by heterogeneous aromatization of the rings and their skeletal rearrangement. The results were compared with GC-MS data from electron ionization.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

REFERENCES

  1. W. G. Ewing, Analytical Instrumentation Handbook, 2nd Ed., M. Dekker, New York (1997), 1453.

    Google Scholar 

  2. K. Pfleger, H. H. Maurer, and A. Weber, Mass-Spectral and GC Data of Drugs, Poisons, Pesticides, Pollutants and Their Metabolites, 2nd Ed., VCH, Weinheim, New York (1992), 653.

    Google Scholar 

  3. E. Ya. Zandberg and U. Kh. Rasulev, Usp. Khim., 51, 1425 (1982).

    Google Scholar 

  4. U. Kh. Rasulev and E. Ya. Zandberg, Prog. Surf. Sci., 28, 181 (1988).

    Google Scholar 

  5. U. Kh. Rasulev, U. Khasanov, and V. V. Palitsin, J. Chromatogr. A, 896, 3 (2000).

    Google Scholar 

  6. A. Ishii, K. Watanabe-Suzuki, H. Seno, Y. Katsumata, and O. Suzuki, J. Chromatogr. B, 758, 117 (2002).

    Google Scholar 

  7. T. Fujii, Eur. Mass Spectrom., 2, 91 (1996).

    Google Scholar 

  8. E. Ya. Zandberg and U. Kh. Rasulev, Teor. Eksp. Khim., 6, 658 (1972).

    Google Scholar 

  9. H. Seno, H. Hattori, S. Kurono, T. Yamada, H. Kumizawa, A. Ishii, and O. Suzuki, J. Chromatogr. B, 673, 189 (1995).

    Google Scholar 

  10. U. Kh. Rasulev, E. G. Nazarov, B. N. Nosirov, and G. T. Rakhmanov, Khim. Prir. Soedin., 70 (1998).

Download references

Author information

Authors and Affiliations

  1. Academy of Sciences of the Republic of Uzbekistan, U. A. Arifov Institute of Electronics, Tashkent

    D. T. Usmanov, U. Khasanov & U. Kh. Rasulev

Authors
  1. D. T. Usmanov
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. U. Khasanov
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. U. Kh. Rasulev
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Usmanov, D.T., Khasanov, U. & Rasulev, U.K. Surface-Ionization Mass Spectrometry of Opium Alkaloids. Chemistry of Natural Compounds 39, 489–494 (2003). https://doi.org/10.1023/B:CONC.0000011126.68733.19

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1023/B:CONC.0000011126.68733.19

Search

Navigation