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Synthesis of Arylidene Derivatives of 1-Aryl-3H-pyrrol-2-ones

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

The aminolysis of 5-aryl-3-arylidene-3H-furan-2-ones by the action of aromatic amines leads to the formation of substituted amides of 4-oxo acids, the subsequent azacyclization of which in the presence of acetic anhydride leads to the formation of 1,5-diaryl-substituted 3-arylidene-3H-pyrrol-2-ones. The mechanism of the occurring and alternative transformations is discussed.

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Egorova, A.Y., Nesterova, V.V. Synthesis of Arylidene Derivatives of 1-Aryl-3H-pyrrol-2-ones. Chemistry of Heterocyclic Compounds 40, 1002–1006 (2004). https://doi.org/10.1023/B:COHC.0000046688.92309.b0

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  • DOI: https://doi.org/10.1023/B:COHC.0000046688.92309.b0

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