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Synthesis of 2-Aryl and 2-Hetaryl Derivatives of 2'-Aminospiro[(1,3-dioxane)-5,5'-thiazolin]-4'-one and Spiro[(1,3-dioxane)-5,5'-thiazolidine]2',4'-dione

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

2-(Het)aryl derivatives of 2'-aminospiro[(1,3-dioxane)-5,5'-thiazolin]-4'-one or spiro[(1,3-dioxane)-5,5'-thiazolidine]-2',4'-dione are formed by the acid catalyzed interaction of 2-amino-5,5-bis(hydroxymethyl)-4-thiazolinone or its oxo analog 5,5-bis(hydroxymethyl)thiazolidine-2,4-dione with (hetero)aromatic aldehydes.

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REFERENCES

  1. K. Buler and D. Pearson. Organic Syntheses [Russian translation], Mir, Moscow (1973), 1, p. 582.

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  2. S. M. Ramsh and A. G. Ivanenko. Khim. Geterotsikl. Soed.,1743 (2003).

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Authors
  1. S. M. Ramsh
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  2. A. G. Ivanenko
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  3. V. A. Shpilyovy
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  4. N. L. Medvedskiy
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  5. P. M. Kushakova
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Ramsh, S.M., Ivanenko, A.G., Shpilyovy, V.A. et al. Synthesis of 2-Aryl and 2-Hetaryl Derivatives of 2'-Aminospiro[(1,3-dioxane)-5,5'-thiazolin]-4'-one and Spiro[(1,3-dioxane)-5,5'-thiazolidine]2',4'-dione. Chemistry of Heterocyclic Compounds 40, 919–926 (2004). https://doi.org/10.1023/B:COHC.0000044576.75311.08

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  • DOI: https://doi.org/10.1023/B:COHC.0000044576.75311.08

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