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Chemistry of Heterocyclic Compounds

, Volume 40, Issue 5, pp 667–675 | Cite as

Reaction of 2-Aminothiazoles and Their Benzo- and Naphtho Derivatives with β-Sulfonyltrifluoromethylvinyldiols

  • A. L. Krasovsky
  • A. M. Moiseev
  • V. G. Nenajdenko
  • E. S. Balenkova
Article

Abstract

By cyclocondensation of 2-aminothiazoles and their benzo and naphtho analogs with β-sulfonyltrifluoromethylvinyldiols, we have obtained a series of novel CF3-containing 6,7-dihydro-5H-[1,3]thiazolo[3,2-a]pyrimidines. In the case of the sterically hindered 2-aminothiazoles, heterocyclization does not occur and the corresponding enamino ketones are formed.

2-aminothiazoles 6,7-dihydro-5H-[1,3]thiazolo[3,2-a]pyrimidines β-sulfonyltrifluoromethylvinyldiols cyclocondensation 

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Copyright information

© Plenum Publishing Corporation 2004

Authors and Affiliations

  • A. L. Krasovsky
    • 1
  • A. M. Moiseev
    • 1
  • V. G. Nenajdenko
    • 1
  • E. S. Balenkova
    • 1
  1. 1.M. V. Lomonosov Moscow State UniversityMoscowRussia

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