Abstract
The catalytic dehydrocyclization of dimethyl(5-methyl-2-thienyl)(2,4-dimethylphenyl)silane accompanied by a skeletal rearrangement gives 2,4,4,7-tetramethyl-4,9-dihydro-4-silanaphtho[3,2-b]thiophene, which was oxidized to 2,4,4,7-tetramethyl-4-silanaphtho[3,2-b]thiophen-9-one, whose structure was solved by X-ray diffraction structural analysis. Various chemical transformations of the ketone synthesized were performed including radical bromination by bromosuccinimide, condensation with furfural in the presence of KOH, reduction by LiAlH4, and nitration by acetyl nitrate.
Similar content being viewed by others
REFERENCES
V. M. Polosin, A. A. Astakhov, A. V. Ivashchenko, M. A. Ryashentseva, E. P. Belanova, A. S. Shashkov, and Kh. M. Minachev, Khim. Geterotsikl. Soedin., 419 (1989).
V. M. Polosin, A. A. Astakhov, V. A. Tafeenko, and A. V. Ivashchenko, Zh. Obshch. Khim., 60, 1580 (1990).
V. M. Polosin, A. A. Astakhov, V. A. Tafeenko, and A. V. Ivashchenko, Metalloorg. Khim., 3, 650 (1990).
A. Gordon and R. Ford, Chemist's Handbook [Russian translation], Mir, Moscow (1976), p. 541.
A. Terney, Modern Organic Chemistry [Russian translation], Vol. 2, Mir, Moscow (1981), p. 651.
M. M. Sergeev, NMR Spectroscopy [in Russian], Izd. Moskovsk. Gos. Univ., Moscow (1981), p. 279.
N. S. Prostakov, Islam Nazrul, and A. V. Varlamov, Khim. Geterotsikl. Soedin., 1528 (1985).
R. A. Benkeser and P. E. Brumfield, J. Am. Chem. Soc., 73, 4770 (1951).
V. M. Polosin, A. A. Astakhov, V. A. Tafeenko, and A. V. Ivashchenko, Zh. Obshch. Khim., 62, 367 (1992).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Polosin, V.M., Astakhov, A.A. & Ryashentseva, M.A. Synthesis and Transformations of 2,4,4,7-Tetramethyl-4-silanaphtho[3,2-b]thiophen-9-one. Chemistry of Heterocyclic Compounds 39, 1249–1254 (2003). https://doi.org/10.1023/B:COHC.0000008275.26329.56
Issue Date:
DOI: https://doi.org/10.1023/B:COHC.0000008275.26329.56