Abstract
Background: With faster image acquisition times and thinner slice widths, multislice detector computed tomography (MSCT) allows visualization of human coronary arteries. Significantly improved image quality, with high resolution and new software for three-dimensional post-processing, has made non-invasive examination of the cavities within human body possible. Objective: The aims of this study are to evaluate the diagnostic accuracy of ECG-gated MSCT for the detection of significant coronary artery stenosis and occlusions. Methods: In 25 patients (19 male and 6 female aged 65 ± 9 years) with suspected obstructive coronary artery disease, ECG-gated MSCT angiography was performed with an 8-slice MSCT scanner. Visual coronary arteries were simulated in three coronary arteries. Conventional coronary angio-graphies were performed in all patients. And coronary lesions in MSCT were estimated by two observers, who did not know the results of the coronary angiography. Results: Current MSCT allows visual coronary artery with good image quality. The overall sensitivity for diagnosing significant coronary stenosis were 75.0%, the specificity was 95.6%. The positive and negative predictive values were 84.9 and 92.2%, respectively. The accuracy of MSCT for detecting coronary stenosis is the highest in the left main tranck and left anterior descending coronary artery, and lowest in the circumflex coronary artery. Conclusion: MSCT was feasible for the detection of coronary artery stenosis.
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Adams D, Fraser D, Abrams H. The complications of coronary arteriography. Circulation 1973; 48: 609–618.
Rensing B, Bongaerts A, van Geuns R, van Ooijen P, Oudkerk M, de Feyter P. Intravenous coronary angiography by electron beam computed tomography: a clinical evaluation. Circulation 1998; 98: 2509–2512.
Achenbach S, Moshage W, Ropers D, Nossen J, Daniel W. Value of electron-beam computed tomography for the noninvasive detection of high-grade coronary-artery stenoses and occlusions. N Engl J Med 1998; 339: 1964–1971.
Nieman K, Oudkerk M, Rensing BJ, et al. Coronary angiography with multi-slice computed tomography. Lancet 2001; 90: 599–603.
Anno H, Kondo T, Hishida H. Multislice helical CT, 3DCT (coronary angiography). Nippon Rinsho 2003; 61: 266–272.
Austen WG, Edwards JE, Frye RL, et al. A reporting system on patients evaluated for coronary artery disease. Report of the Ad Hoc Committee for Grading of Coronary Artery Disease, Council on Cardiovascular Surgery, American Heart Association. Circulation 1975; 51: 5–40.
Matsuo S, Takahashi M, Nakamura Y, Kinoshita M. Evaluation of cardiac sympathetic innervation with iodine-123-metaiodobenzylguanidine imaging in patients with silent myocardial ischemia. J Nucl Med 1996; 37: 712–717.
Nieman K, Rensing BJ, van Geuns RJ, et al. Usefulness of multislice computed tomography for detecting obstructive coronary artery disease. Am J Cardiol 2002; 89: 913–918.
Achenbach S, Giesler T, Ropers D, et al. Detection of coronary artery stenoses by contrast-enhanced, retrospectively electrocardiographically-gated, multislice spiral computed tomography. Circulation 2001; 103: 2535–2538.
Matsuo S, Nakamura Y, Kinoshita M. Post-stress left ventricular function in patients with coronary artery disease using thallium-201 ECG-gated single-photon emission tomography. Exp Clin Cardiol 2002; 7: 30–34.
Knez A, Becker C, Becker A, et al. Determination of coronary calcium with multi-slice spiral computed tomography: a comparative study with electron-beam CT. Int J Cardiovasc Imaging 2002; 18: 295–303.
Cohnen M, Poll L, Puettman C, Ewen K, Saleh A, Mödder U. Effective doses in standard protocols for multi-slice CT scanning. Eur Radiol 2003; 13: 1148–1153.
Ohnesorge B, Flohr T, Becher A, Reiser M. Dose evaluation and dose reduction strategies for ECG-gated multislice spiral CT of the heart. Radiology 2000; 217: 487.
Chonen M, Poli L, Pütterman C, Ewen K, Mödder U. Radiation exposure in multi-slice of the heart. Fortschr Röntgenstr 2001; 173: 295–299.
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Matsuo, S., Nakamura, Y., Matsumoto, T. et al. Visual assessment of coronary artery stenosis with electrocardiographically-gated multislice computed tomography. Int J Cardiovasc Imaging 20, 61–66 (2004). https://doi.org/10.1023/B:CAIM.0000013159.01950.7c
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DOI: https://doi.org/10.1023/B:CAIM.0000013159.01950.7c