Skip to main content
SpringerLink
Log in

Population-Based Statistics for Women Diagnosed with Inflammatory Breast Cancer (United States)

  • Published:
Cancer Causes & Control Aims and scope Submit manuscript

Abstract

Objective: The purpose of this study was to use population-based information to describe the demographic and tumor characteristics of inflammatory breast cancer (IBC)– the most aggressive form of this disease.

Methods: IBC cases diagnosed during 1994 through 1998 were reported to 26 population-based cancer registries covering approximately 40% of the US population. Rates were expressed per 100,000 female population and age-adjusted to the 2000 US population. Ninety-five percent gamma confidence limits were estimated for the rates.

Results: Among the 3626 women diagnosed with IBC during 1994–1998, the majority were 40–59 years old. Most tumors were diagnosed at a regional (68.9%) or distant (25.3%) stage and were poorly differentiated (49.4%). The rate of IBC was 1.3 per 100,000 for all races combined. Black women had the highest risk (1.6) and Asian and Pacific Islander women the lowest (0.7).

Conclusions: IBC is an extremely rare form of breast cancer. More precise diagnostic criteria are needed to distinguish it from less aggressive forms of the disease. Future studies should use a population-based design and collect detailed clinical information, including the presence of erythema, edema or peau d'orange appearance of the skin, and other clinical signs of disease.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Levine PH, Steinhorn SC, Ries LG, Aron JL (1985) Inflammatory breast cancer: the experience of the surveillance, epidemiology, and end results (SEER) program. J Natl Cancer Inst 74: 291–297.

    PubMed  Google Scholar 

  2. Margoles RG, Fisher B, Hortobagyi H, Bloomer WG (2000) Neoplasms of the breast. In: Bast RC, Kufe DW, Pollock RE, Weichselbaum RR, Holland JF, Frei E, eds. Cancer Medicine, 5th edn. Hamilton, Ontario: B.C. Decker Inc.

    Google Scholar 

  3. Jaiyesimi IA, Buzdar AU, Hortobagyi G (1992) Inflammatory breast cancer: a review. J Clin Oncol 10: 1014–1024.

    PubMed  Google Scholar 

  4. Chang S, Parker SL, Pham T, Buzdar AU, Hursting SD (1998) Inflammatory breast carcinoma incidence and survival, the surveillance, epidemiology, and end results program of the National Cancer Institute, 1975-1992. Cancer 82(12): 2366–2372.

    PubMed  Google Scholar 

  5. Taylor G, Meltzer A (1938) Inflammatory carcinoma of the breast. Am J Cancer 33: 33–49.

    Google Scholar 

  6. Haagensen C (1971) Diseases of the Breast, 2nd edn. Philadelphia, PA: Saunders, pp. 576–584.

    Google Scholar 

  7. Singletary SE, Ames FC, Buzdar AU (1994) Management of inflammatory breast cancer. World J Surg 18: 87–92.

    PubMed  Google Scholar 

  8. Bonnier P, Charpin C, Lejeune C, et al. (1995) Inflammatory carcinomas of the breast: a clinical pathological, or a clinical and pathological definition? Int J Cancer 62: 382–385.

    PubMed  Google Scholar 

  9. Dahlbeck SW, Donnelly JF, Theriault RL (1995) Differentiating inflammatory breast cancer from acute mastitis. Am Fam Physician 52: 929–934.

    PubMed  Google Scholar 

  10. Brooks HL, Mandava N, Pizzi W, Shah S (1998) Inflammatory breast carcinoma: a community hospital experience. Am College Surgeons 186: 622–629.

    Google Scholar 

  11. Percy C, Van Holten V, Muir C, eds. (1990) International Classification of Diseases for Oncology, 2nd edn. Geneva, Switzerland: World Health Organization.

    Google Scholar 

  12. Chang S, Buzdar AU, Hursting SD (1998) Inflammatory breast cancer and body mass index. J Clin Oncol 16: 3731–3735.

    PubMed  Google Scholar 

  13. SEER*Stat 2001(2003) Bethesda, MD: National Cancer Institute. Also available from: URL: http://seer.cancer.gov/seerstat [accessed 2003, January 13].

  14. Fay MP, Feuer EJ (1997) Confidence intervals for directly standardized rates: a method based on the gamma distribution. Statist Med 16: 791–801.

    Google Scholar 

  15. Ries LAG, Eisner MP, Kosary CL, et al. eds. (2002) SEER Cancer Statistics Review, 1973-1999. Bethesda, MD: National Cancer Institute. Also available from: URL: http://www.seer.cancer.gov/csr/1973_1999 [accessed 2002, June 14].

    Google Scholar 

  16. Katz D, Baptista J, Azen SP, Pike MC (1978) Obtaining confidence intervals for the risk ratio in cohort studies. Biometrics 34: 469–474.

    Google Scholar 

  17. O'Malley C, Hu KU, West DW (2002) North American association of central cancer registries: race and ethnicity identifier assessment project. Also available from: URL http://www.naaccr.org, http://www.naaccr.org/Training/files [accessed August 2002].

  18. Ries LAG, Eisner MP, Kosary CL, et al. eds. (2001) SEER Cancer Statistics Review, 1973-1998. Bethesda, MD: National Cancer Institute.

    Google Scholar 

  19. Greene FL, Page DL, Fleming ID, et al. eds. (2002) AJCC Cancer Staging Manual, 6th edn. New York: Springer-Verlag, pp. 221–240.

    Google Scholar 

  20. US Cancer Statistics Working Group (2002) United States Cancer Statistics: 1999 Incidence. Atlanta, GA: Department of Health and Human Services, Centers for Disease Control and Prevention and National Cancer Institute.

    Google Scholar 

  21. Rosenberg HM, Maurer JD, Sorlie PD, et al.(1999) Quality of death rates by race and Hispanic origin: a summary of current research. Vital Health Stat 2(128).

  22. Poe GS, Powell-Griner E, McLaughlin JK, Placek PJ, Thompson GB, Robinson K (1993) Comparability of the Death Certificate and the 1986 National Mortality Followback Survey. Hyattsville, MD: National Center for Health Statistics.

    Google Scholar 

  23. Kolonel LH, Goodman MT (1992) Racial variation in cancer: fact or artifact? J Natl Cancer Inst 84: 916–917.

    Google Scholar 

  24. Hogan H (1993) The 1990 post-enumeration survey: operations and results. J Am Stat Assoc 88: 1047–1060.

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Division of Cancer Prevention and Control, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, 4770 Buford Highway NE, MS K53, Chamblee, GA, 30341-3717, USA

    Phyllis A. Wingo & Patricia M. Jamison

  2. Rollins School of Public Health, Emory University, Atlanta, GA, USA

    John L. Young

  3. Division of Epidemiology and Surveillance, National Immunization Program, Atlanta, GA, USA

    Paul Gargiullo

Authors
  1. Phyllis A. Wingo
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Patricia M. Jamison
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. John L. Young
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Paul Gargiullo
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Phyllis A. Wingo.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Wingo, P.A., Jamison, P.M., Young, J.L. et al. Population-Based Statistics for Women Diagnosed with Inflammatory Breast Cancer (United States). Cancer Causes Control 15, 321–328 (2004). https://doi.org/10.1023/B:CACO.0000024222.61114.18

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1023/B:CACO.0000024222.61114.18

Search

Navigation