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Single-step recovery of ephedrine hydrochloride from raw materials using expanded bed adsorption


Expanded bed adsorption, using a cation resin 001×7 Styrene-DVB, was used to recover and purify ephedrine hydrochloride from a powdered herb. The axial liquid-phase dispersion coefficient was about 10−5 m2 s−1 and the recovery yield and purification reached 86% and 22, respectively. Compared with using conventional extraction with dimethylbenzene, this method is safer and also more efficient.

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Correspondence to Zhi-Guo Su.

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Chen, WD., Wang, YD., Zha, Lh. et al. Single-step recovery of ephedrine hydrochloride from raw materials using expanded bed adsorption. Biotechnology Letters 26, 1233–1236 (2004).

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  • cation resin
  • chromatography
  • ephedrine hydrochloride
  • expanded bed adsorption