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In Vitro Effect of Acetylcholine on Function of Sinoatrial Node in Rat Heart

Bulletin of Experimental Biology and Medicine volume 138, pages 192–193 (2004)Cite this article

Abstract

Electrophysiological parameters of true pacemakers in the sinoatrial node of rat heart were recorded intracellularly using glass microelectrodes. In 11 of 13 experiments acetylcholine in increasing doses did not induce migration of the dominant pacemaker region, while in two cases its minor migration upstream the sinus node artery was observed.

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Affiliations

  1. Department of Morphology, Russian State Medical University, Moscow

    P. V. Sutyagin, E. E. Kalinina & A. S. Pylaev

Authors
  1. P. V. Sutyagin
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  2. E. E. Kalinina
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  3. A. S. Pylaev
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Sutyagin, P.V., Kalinina, E.E. & Pylaev, A.S. In Vitro Effect of Acetylcholine on Function of Sinoatrial Node in Rat Heart. Bulletin of Experimental Biology and Medicine 138, 192–193 (2004). https://doi.org/10.1023/B:BEBM.0000048386.75334.33

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  • DOI: https://doi.org/10.1023/B:BEBM.0000048386.75334.33

  • sinoatrial node
  • pacemaker cells
  • dominant pacemaker region
  • acetylcholine