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In Vitro Effect of Acetylcholine on Function of Sinoatrial Node in Rat Heart

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Abstract

Electrophysiological parameters of true pacemakers in the sinoatrial node of rat heart were recorded intracellularly using glass microelectrodes. In 11 of 13 experiments acetylcholine in increasing doses did not induce migration of the dominant pacemaker region, while in two cases its minor migration upstream the sinus node artery was observed.

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REFERENCES

  1. V. M. Adomonis, Yu. Yu. Bredikis, F. F. Bukauskas, et al., Byull. Eksp. Biol. Med., 103, No. 4, 387–390 (1987).

    Google Scholar 

  2. E. E. Kalinina, P. V. Sutyagin, and A. S. Pylaev, Ibid., 125, No. 3, 337–339 (1998).

    Google Scholar 

  3. P. V. Sutyagin, I. A. Chervova, and A. S. Pylaev, Arkh. Anat., Gistol., Embriol., 86, No. 2, 51–57 (1984).

    Google Scholar 

  4. P. V. Sutyagin, I. A. Chervova, and A. S. Pylaev, Kardiologiya, 28, No. 2, 84–88 (1988).

    Google Scholar 

  5. A. J. C. Mackaay, T. Op't Hof, W. K. Bleeker, et al., J. Pharmacol. Exp. Ther., 214, No. 2, 417–422 (1980).

    PubMed  Google Scholar 

  6. Y. Miyashita, Y. Furukawa, K. Nakajima, et al., J. Cardiovasc. Electrophysiol., 10, No. 8, 1066–1076 (1999).

    PubMed  Google Scholar 

  7. N. Shibata, S. Inada, K. Mitsui, et al., J. Exp. Physiol., 86, No. 2, 177–184 (2001).

    Google Scholar 

  8. G. Steinbeck and B. Luderitz, Circulation, 56, No. 3, 402–409 (1977).

    PubMed  Google Scholar 

  9. W. T. Woods, F. Urthaler, and T. N. James, Circ. Res., 39, No. 1, 76–82 (1976).

    PubMed  Google Scholar 

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Authors and Affiliations

  1. Department of Morphology, Russian State Medical University, Moscow

    P. V. Sutyagin, E. E. Kalinina & A. S. Pylaev

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  1. P. V. Sutyagin
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  2. E. E. Kalinina
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  3. A. S. Pylaev
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Sutyagin, P.V., Kalinina, E.E. & Pylaev, A.S. In Vitro Effect of Acetylcholine on Function of Sinoatrial Node in Rat Heart. Bulletin of Experimental Biology and Medicine 138, 192–193 (2004). https://doi.org/10.1023/B:BEBM.0000048386.75334.33

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  • DOI: https://doi.org/10.1023/B:BEBM.0000048386.75334.33

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