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Disorders in Restructuring of T-Cell Receptor γ-Chain in Malignant Skin Lymphomas

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Abstract

Disorders in restructuring of T-cell receptor γ-chain in DNA from skin biopsy specimens and peripheral blood lymphocyte of patients with malignant skin lymphomas at different stages of the disease were detected by PCR. Nucleotide sequences of monoclonal T-cell receptors were determined. The study showed that DNA sequences from the skin and lymphocytes did not coincide in some cases.

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Authors and Affiliations

  1. Russian State Medical University, Ministry of Health of Russian Federation, Moscow

    M. V. Savvateeva, M. I. Savina, L. I. Markusheva, V. A. Samsonov & R. T. Toguzov

  2. State Central Institute of Skin and Sexually Transmitted Diseases, Ministry of Health of Russian Federation, Moscow

    M. V. Savvateeva, M. I. Savina, L. I. Markusheva, V. A. Samsonov & R. T. Toguzov

Authors
  1. M. V. Savvateeva
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  2. M. I. Savina
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  3. L. I. Markusheva
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  4. V. A. Samsonov
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  5. R. T. Toguzov
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Savvateeva, M.V., Savina, M.I., Markusheva, L.I. et al. Disorders in Restructuring of T-Cell Receptor γ-Chain in Malignant Skin Lymphomas. Bulletin of Experimental Biology and Medicine 138, 179–181 (2004). https://doi.org/10.1023/B:BEBM.0000048382.03906.32

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  • DOI: https://doi.org/10.1023/B:BEBM.0000048382.03906.32

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