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Histochemical Study of Mast Cells from the Thymus of Mice Receiving ACTH1-24

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Abstract

Synthetic ACTH1-24 analogue administered in a daily dose of 0.01 mg/kg decreased the number and size of mast cells and increased intracellular serotonin concentration. ACTH1-24 induced degranulation of young mast cells and release of undersulfated heparin. Correlation analysis showed that hormonal imbalance produced by ACTH1-24 was accompanied by redistribution of bioamines.

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Authors and Affiliations

  1. Laboratory of the Department for Medical Biology, Chuvash State University, Cheboksary

    E. M. Naumova & V. E. Sergeeva

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  1. E. M. Naumova
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  2. V. E. Sergeeva
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Naumova, E.M., Sergeeva, V.E. Histochemical Study of Mast Cells from the Thymus of Mice Receiving ACTH1-24. Bulletin of Experimental Biology and Medicine 138, 93–96 (2004). https://doi.org/10.1023/B:BEBM.0000046949.29614.09

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  • DOI: https://doi.org/10.1023/B:BEBM.0000046949.29614.09

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